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APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis.
Maciejowski J, Chatzipli A, Dananberg A, Chu K, Toufektchan E, Klimczak LJ, Gordenin DA, Campbell PJ, de Lange T. Maciejowski J, et al. Among authors: toufektchan e. Nat Genet. 2020 Sep;52(9):884-890. doi: 10.1038/s41588-020-0667-5. Epub 2020 Jul 27. Nat Genet. 2020. PMID: 32719516 Free PMC article.
ER-directed TREX1 limits cGAS activation at micronuclei.
Mohr L, Toufektchan E, von Morgen P, Chu K, Kapoor A, Maciejowski J. Mohr L, et al. Among authors: toufektchan e. Mol Cell. 2021 Feb 18;81(4):724-738.e9. doi: 10.1016/j.molcel.2020.12.037. Epub 2021 Jan 20. Mol Cell. 2021. PMID: 33476576 Free PMC article.
Epigenetic dysregulation from chromosomal transit in micronuclei.
Agustinus AS, Al-Rawi D, Dameracharla B, Raviram R, Jones BSCL, Stransky S, Scipioni L, Luebeck J, Di Bona M, Norkunaite D, Myers RM, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel PS, Mittal V, Shah SP, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum MF, Koche RP, Sidoli S, Bafna V, David Y, Bakhoum SF. Agustinus AS, et al. Among authors: toufektchan e. Nature. 2023 Jul;619(7968):176-183. doi: 10.1038/s41586-023-06084-7. Epub 2023 Jun 7. Nature. 2023. PMID: 37286593 Free PMC article.
Essential role for centromeric factors following p53 loss and oncogenic transformation.
Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard-Levin ZA, Orsi GA, Simeonova I, Toufektchan E, Attardi LD, Toledo F, Almouzni G. Filipescu D, et al. Among authors: toufektchan e. Genes Dev. 2017 Mar 1;31(5):463-480. doi: 10.1101/gad.290924.116. Epub 2017 Mar 29. Genes Dev. 2017. PMID: 28356341 Free PMC article.
p53 downregulates the Fanconi anaemia DNA repair pathway.
Jaber S, Toufektchan E, Lejour V, Bardot B, Toledo F. Jaber S, et al. Among authors: toufektchan e. Nat Commun. 2016 Apr 1;7:11091. doi: 10.1038/ncomms11091. Nat Commun. 2016. PMID: 27033104 Free PMC article.
11 results