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Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M. Delacher M, et al. Among authors: trager u. Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Nat Immunol. 2017. PMID: 28783152 Free PMC article.
Rbpj expression in regulatory T cells is critical for restraining TH2 responses.
Delacher M, Schmidl C, Herzig Y, Breloer M, Hartmann W, Brunk F, Kägebein D, Träger U, Hofer AC, Bittner S, Weichenhan D, Imbusch CD, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Gröne HJ, Schmid RM, Rehli M, Abramson J, Feuerer M. Delacher M, et al. Among authors: trager u. Nat Commun. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w. Nat Commun. 2019. PMID: 30962454 Free PMC article.
Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells.
Delacher M, Barra MM, Herzig Y, Eichelbaum K, Rafiee MR, Richards DM, Träger U, Hofer AC, Kazakov A, Braband KL, Gonzalez M, Wöhrl L, Schambeck K, Imbusch CD, Abramson J, Krijgsveld J, Feuerer M. Delacher M, et al. Among authors: trager u. iScience. 2020 May 22;23(5):101127. doi: 10.1016/j.isci.2020.101127. Epub 2020 May 4. iScience. 2020. PMID: 32422593 Free PMC article.
Peripheral inflammation in neurodegeneration.
Träger U, Tabrizi SJ. Träger U, et al. J Mol Med (Berl). 2013 Jun;91(6):673-81. doi: 10.1007/s00109-013-1026-0. Epub 2013 Apr 2. J Mol Med (Berl). 2013. PMID: 23546523 Review.
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ. Träger U, et al. Brain. 2014 Mar;137(Pt 3):819-33. doi: 10.1093/brain/awt355. Epub 2014 Jan 22. Brain. 2014. PMID: 24459107 Free PMC article.
18 results