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Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations.
Huie JR, Mondello S, Lindsell CJ, Antiga L, Yuh EL, Zanier ER, Masson S, Rosario BL, Ferguson AR; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators, The Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Participants and Investigators, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Participants and Investigators. Huie JR, et al. J Neurotrauma. 2021 Sep 15;38(18):2514-2529. doi: 10.1089/neu.2019.6762. Epub 2020 Apr 1. J Neurotrauma. 2021. PMID: 32046588 Free PMC article. Review.
Recent biomarker innovations hold potential for transforming diagnosis, prognostic modeling, and precision therapeutic targeting of traumatic brain injury (TBI). ...We focus our discussion around recent experiences from the International Traumatic Brain Injury Research
Recent biomarker innovations hold potential for transforming diagnosis, prognostic modeling, and precision therapeutic targeting of t …
Trajectories of Insomnia in Adults After Traumatic Brain Injury.
Wickwire EM, Albrecht JS, Capaldi VF 2nd, Jain SO, Gardner RC, Werner JK, Mukherjee P, McKeon AB, Smith MT, Giacino JT, Nelson LD, Williams SG, Collen J, Sun X, Schnyer DM, Markowitz AJ, Manley GT, Krystal AD; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Wickwire EM, et al. JAMA Netw Open. 2022 Jan 4;5(1):e2145310. doi: 10.1001/jamanetworkopen.2021.45310. JAMA Netw Open. 2022. PMID: 35080600 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: In this prospective cohort study, latent class mixed models (LCMMs) were used to model insomnia trajectories over time and to classify participants into distinct profile groups. Data from the Transforming Research and Clinical Know …
DESIGN, SETTING, AND PARTICIPANTS: In this prospective cohort study, latent class mixed models (LCMMs) were used to model insomnia trajector …
Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.
Okonkwo DO, Puffer RC, Puccio AM, Yuh EL, Yue JK, Diaz-Arrastia R, Korley FK, Wang KKW, Sun X, Taylor SR, Mukherjee P, Markowitz AJ, Jain S, Manley GT; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Okonkwo DO, et al. J Neurotrauma. 2020 Dec 1;37(23):2460-2467. doi: 10.1089/neu.2020.7140. Epub 2020 Sep 14. J Neurotrauma. 2020. PMID: 32854584 Free PMC article.
This phase 1 biomarker cohort analysis of the multi-center, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study compares GFAP's diagnostic performance, measured on a rapid point-of-care platform, against protein S10 …
This phase 1 biomarker cohort analysis of the multi-center, observational Transforming Research and Clinical Knowledge in Trau …
Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.
Williams JR, Nieblas-Bedolla E, Feroze A, Young C, Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL; and The Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Williams JR, et al. Neurocrit Care. 2021 Oct;35(2):335-346. doi: 10.1007/s12028-021-01263-8. Epub 2021 Jul 26. Neurocrit Care. 2021. PMID: 34309784 Free PMC article.
To address this, retrospective data on patients from the multicenter prospective Transforming Research and Clinical Knowledge in TBI study were studied. ...
To address this, retrospective data on patients from the multicenter prospective Transforming Research and Clinical Knowledge …
GFAP-BDP as an acute diagnostic marker in traumatic brain injury: results from the prospective transforming research and clinical knowledge in traumatic brain injury study.
Okonkwo DO, Yue JK, Puccio AM, Panczykowski DM, Inoue T, McMahon PJ, Sorani MD, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Manley GT; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Okonkwo DO, et al. J Neurotrauma. 2013 Sep 1;30(17):1490-7. doi: 10.1089/neu.2013.2883. Epub 2013 Aug 1. J Neurotrauma. 2013. PMID: 23489259 Free PMC article. Clinical Trial.
Here, we evaluate the diagnostic accuracy of elevated levels of plasma GFAP-BDP in TBI. Participants were identified as part of the prospective Transforming Research And Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study. ...Although these findings confi …
Here, we evaluate the diagnostic accuracy of elevated levels of plasma GFAP-BDP in TBI. Participants were identified as part of the prospect …
Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research.
Kreitzer N, Jain S, Young JS, Sun X, Stein MB, McCrea MA, Levin HS, Giacino JT, Markowitz AJ, Manley GT, Nelson LD; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators. Kreitzer N, et al. J Neurotrauma. 2021 Dec;38(23):3352-3363. doi: 10.1089/neu.2020.7546. Epub 2021 Oct 18. J Neurotrauma. 2021. PMID: 34435894 Free PMC article.
The findings imply that, as compared with the SWLS, the QOLIBRI-OS appears to identify QoL issues more specifically relevant to traumatically injured patients and may be a more appropriate primary QoL outcome measure for research focused on the sequelae of traumatic injuri …
The findings imply that, as compared with the SWLS, the QOLIBRI-OS appears to identify QoL issues more specifically relevant to traumaticall …
Correction to: Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.
Williams JR, Nieblas-Bedolla E, Feroze A, Young C, Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK‑TBI) Investigators. Williams JR, et al. Neurocrit Care. 2021 Dec;35(3):927. doi: 10.1007/s12028-021-01356-4. Neurocrit Care. 2021. PMID: 34591257 No abstract available.