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Identification of High-Potency Human TLR8 and Dual TLR7/TLR8 Agonists in Pyrimidine-2,4-diamines.
J Med Chem. 2017 Mar 9;60(5):2084-2098. doi: 10.1021/acs.jmedchem.6b01860. Epub 2017 Feb 15.
J Med Chem. 2017.
PMID: 28146629
Human Toll-like Receptor (TLR) 8-Specific Agonistic Activity in Substituted Pyrimidine-2,4-diamines.
Beesu M, Salyer AC, Trautman KL, Hill JK, David SA.
Beesu M, et al. Among authors: trautman kl.
J Med Chem. 2016 Sep 8;59(17):8082-93. doi: 10.1021/acs.jmedchem.6b00872. Epub 2016 Aug 19.
J Med Chem. 2016.
PMID: 27513008
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Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue.
Yoo E, Salyer ACD, Brush MJH, Li Y, Trautman KL, Shukla NM, De Beuckelaer A, Lienenklaus S, Deswarte K, Lambrecht BN, De Geest BG, David SA.
Yoo E, et al. Among authors: trautman kl.
Bioconjug Chem. 2018 Aug 15;29(8):2741-2754. doi: 10.1021/acs.bioconjchem.8b00386. Epub 2018 Jul 17.
Bioconjug Chem. 2018.
PMID: 29969553
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Identification of Human Toll-like Receptor 2-Agonistic Activity in Dihydropyridine-Quinolone Carboxamides.
Hu Z, Banothu J, Beesu M, Gustafson CJ, Brush MJH, Trautman KL, Salyer ACD, Pathakumari B, David SA.
Hu Z, et al. Among authors: trautman kl.
ACS Med Chem Lett. 2018 Dec 20;10(1):132-136. doi: 10.1021/acsmedchemlett.8b00540. eCollection 2019 Jan 10.
ACS Med Chem Lett. 2018.
PMID: 30655960
Free PMC article.
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