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Heparin mimetics with anticoagulant activity.
Nahain AA, Ignjatovic V, Monagle P, Tsanaktsidis J, Ferro V. Nahain AA, et al. Among authors: tsanaktsidis j. Med Res Rev. 2018 Sep;38(5):1582-1613. doi: 10.1002/med.21489. Epub 2018 Feb 15. Med Res Rev. 2018. PMID: 29446104 Review.
Anticoagulant Heparin Mimetics via RAFT Polymerization.
Nahain AA, Ignjatovic V, Monagle P, Tsanaktsidis J, Vamvounis G, Ferro V. Nahain AA, et al. Among authors: tsanaktsidis j. Biomacromolecules. 2020 Feb 10;21(2):1009-1021. doi: 10.1021/acs.biomac.9b01688. Epub 2019 Dec 30. Biomacromolecules. 2020. PMID: 31841320
Structure-activity relationship studies of SEN12333 analogues: determination of the optimal requirements for binding affinities at α7 nAChRs through incorporation of known structural motifs.
Beinat C, Reekie T, Banister SD, O'Brien-Brown J, Xie T, Olson TT, Xiao Y, Harvey A, O'Connor S, Coles C, Grishin A, Kolesik P, Tsanaktsidis J, Kassiou M. Beinat C, et al. Among authors: tsanaktsidis j. Eur J Med Chem. 2015 May 5;95:277-301. doi: 10.1016/j.ejmech.2015.03.025. Epub 2015 Mar 14. Eur J Med Chem. 2015. PMID: 25827398
Cubane: 50 years later.
Biegasiewicz KF, Griffiths JR, Savage GP, Tsanaktsidis J, Priefer R. Biegasiewicz KF, et al. Among authors: tsanaktsidis j. Chem Rev. 2015 Jul 22;115(14):6719-45. doi: 10.1021/cr500523x. Epub 2015 Jun 23. Chem Rev. 2015. PMID: 26102302 Review. No abstract available.
Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.
Chalmers BA, Xing H, Houston S, Clark C, Ghassabian S, Kuo A, Cao B, Reitsma A, Murray CE, Stok JE, Boyle GM, Pierce CJ, Littler SW, Winkler DA, Bernhardt PV, Pasay C, De Voss JJ, McCarthy J, Parsons PG, Walter GH, Smith MT, Cooper HM, Nilsson SK, Tsanaktsidis J, Savage GP, Williams CM. Chalmers BA, et al. Among authors: tsanaktsidis j. Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3580-5. doi: 10.1002/anie.201510675. Epub 2016 Feb 5. Angew Chem Int Ed Engl. 2016. PMID: 26846616
The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement.
Houston SD, Fahrenhorst-Jones T, Xing H, Chalmers BA, Sykes ML, Stok JE, Farfan Soto C, Burns JM, Bernhardt PV, De Voss JJ, Boyle GM, Smith MT, Tsanaktsidis J, Savage GP, Avery VM, Williams CM. Houston SD, et al. Among authors: tsanaktsidis j. Org Biomol Chem. 2019 Jul 17;17(28):6790-6798. doi: 10.1039/c9ob01238a. Org Biomol Chem. 2019. PMID: 31241113
20 results