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Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.
Serebrennikova OB, Tsatsanis C, Mao C, Gounaris E, Ren W, Siracusa LD, Eliopoulos AG, Khazaie K, Tsichlis PN. Serebrennikova OB, et al. Among authors: tsichlis pn. Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1082-91. doi: 10.1073/pnas.1115098109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451924 Free PMC article.
AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing.
Laliotis GI, Chavdoula E, Paraskevopoulou MD, Kaba A, La Ferlita A, Singh S, Anastas V, Nair KA 2nd, Orlacchio A, Taraslia V, Vlachos I, Capece M, Hatzigeorgiou A, Palmieri D, Tsatsanis C, Alaimo S, Sehgal L, Carbone DP, Coppola V, Tsichlis PN. Laliotis GI, et al. Among authors: tsichlis pn. Nat Commun. 2021 Jul 30;12(1):4624. doi: 10.1038/s41467-021-24795-1. Nat Commun. 2021. PMID: 34330897 Free PMC article. Retracted.
AKT Isoforms in Macrophage Activation, Polarization, and Survival.
Lapi I, Daskalaki MG, Axarlis K, Paflioti E, Tsichlis PN, Vergadi E, Tsatsanis C. Lapi I, et al. Among authors: tsichlis pn. Curr Top Microbiol Immunol. 2022;436:165-196. doi: 10.1007/978-3-031-06566-8_7. Curr Top Microbiol Immunol. 2022. PMID: 36243844
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.
Arranz A, Doxaki C, Vergadi E, Martinez de la Torre Y, Vaporidi K, Lagoudaki ED, Ieronymaki E, Androulidaki A, Venihaki M, Margioris AN, Stathopoulos EN, Tsichlis PN, Tsatsanis C. Arranz A, et al. Among authors: tsichlis pn. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9517-22. doi: 10.1073/pnas.1119038109. Epub 2012 May 30. Proc Natl Acad Sci U S A. 2012. PMID: 22647600 Free PMC article.
223 results