Tsichlis PN - Search Results

1

A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.

Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K. Hirsch HA, et al. Among authors: tsichlis pn. Cancer Cell. 2010 Apr 13;17(4):348-61. doi: 10.1016/j.ccr.2010.01.022. Cancer Cell. 2010. PMID: 20385360 Free PMC article.

2

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.

Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Hirsch HA, et al. Among authors: tsichlis pn. Cancer Res. 2009 Oct 1;69(19):7507-11. doi: 10.1158/0008-5472.CAN-09-2994. Epub 2009 Sep 14. Cancer Res. 2009. PMID: 19752085 Free PMC article.

3

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells.

Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Iliopoulos D, et al. Among authors: tsichlis pn. Mol Cell. 2010 Sep 10;39(5):761-72. doi: 10.1016/j.molcel.2010.08.013. Mol Cell. 2010. PMID: 20832727 Free PMC article.

4

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Polytarchou C, et al. Among authors: tsichlis pn. Cancer Res. 2011 Jul 1;71(13):4720-31. doi: 10.1158/0008-5472.CAN-11-0365. Epub 2011 May 9. Cancer Res. 2011. PMID: 21555366 Free PMC article.

5

MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.

Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. Iliopoulos D, et al. Among authors: tsichlis pn. Sci Signal. 2009 Oct 13;2(92):ra62. doi: 10.1126/scisignal.2000356. Sci Signal. 2009. PMID: 19825827 Free PMC article.

6

Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.

Sanidas I, Polytarchou C, Hatziapostolou M, Ezell SA, Kottakis F, Hu L, Guo A, Xie J, Comb MJ, Iliopoulos D, Tsichlis PN. Sanidas I, et al. Among authors: tsichlis pn. Mol Cell. 2014 Feb 20;53(4):577-90. doi: 10.1016/j.molcel.2013.12.018. Epub 2014 Jan 23. Mol Cell. 2014. PMID: 24462114 Free PMC article.

7

MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.

Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. Polytarchou C, et al. Among authors: tsichlis pn. Gastroenterology. 2015 Oct;149(4):981-92.e11. doi: 10.1053/j.gastro.2015.05.057. Epub 2015 Jun 6. Gastroenterology. 2015. PMID: 26055138 Free PMC article.

8

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.

Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C. Androulidaki A, et al. Among authors: tsichlis pn. Immunity. 2009 Aug 21;31(2):220-31. doi: 10.1016/j.immuni.2009.06.024. Immunity. 2009. PMID: 19699171 Free PMC article.

9

Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.

Maroulakou IG, Oemler W, Naber SP, Tsichlis PN. Maroulakou IG, et al. Among authors: tsichlis pn. Cancer Res. 2007 Jan 1;67(1):167-77. doi: 10.1158/0008-5472.CAN-06-3782. Cancer Res. 2007. PMID: 17210696

10

Histone demethylases and cancer.

Kampranis SC, Tsichlis PN. Kampranis SC, et al. Among authors: tsichlis pn. Adv Cancer Res. 2009;102:103-69. doi: 10.1016/S0065-230X(09)02004-1. Adv Cancer Res. 2009. PMID: 19595308 Free PMC article. Review.

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