Tutt A - Search Results

1

Therapeutic potential of PARP inhibitors for metastatic breast cancer.

Irshad S, Ashworth A, Tutt A. Irshad S, et al. Among authors: tutt a. Expert Rev Anticancer Ther. 2011 Aug;11(8):1243-51. doi: 10.1586/era.11.52. Expert Rev Anticancer Ther. 2011. PMID: 21916578 Review.

2

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.

Tutt A, Ashworth A. Tutt A, et al. Trends Mol Med. 2002 Dec;8(12):571-6. doi: 10.1016/s1471-4914(02)02434-6. Trends Mol Med. 2002. PMID: 12470990 Review.

3

Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity.

Tutt A, Connor F, Bertwistle D, Kerr P, Peacock J, Ross G, Ashworth A. Tutt A, et al. Oncogene. 2003 May 15;22(19):2926-31. doi: 10.1038/sj.onc.1206522. Oncogene. 2003. PMID: 12771943

4

Close relatives or distant cousins?

Tutt A, Ashworth A. Tutt A, et al. Lancet Oncol. 2003 Oct;4(10):593-4. doi: 10.1016/s1470-2045(03)01217-8. Lancet Oncol. 2003. PMID: 14554235 No abstract available.

5

Hallmarks of 'BRCAness' in sporadic cancers.

Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: tutt a. Nat Rev Cancer. 2004 Oct;4(10):814-9. doi: 10.1038/nrc1457. Nat Rev Cancer. 2004. PMID: 15510162 Review.

6

Targeting the DNA repair defect of BRCA tumours.

Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: tutt a. Curr Opin Pharmacol. 2005 Aug;5(4):388-93. doi: 10.1016/j.coph.2005.03.006. Curr Opin Pharmacol. 2005. PMID: 15955736 Review.

7

Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer.

Tutt AN, Lord CJ, McCabe N, Farmer H, Turner N, Martin NM, Jackson SP, Smith GC, Ashworth A. Tutt AN, et al. Cold Spring Harb Symp Quant Biol. 2005;70:139-48. doi: 10.1101/sqb.2005.70.012. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869747

8

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition.

McCabe N, Turner NC, Lord CJ, Kluzek K, Bialkowska A, Swift S, Giavara S, O'Connor MJ, Tutt AN, Zdzienicka MZ, Smith GC, Ashworth A. McCabe N, et al. Among authors: tutt an. Cancer Res. 2006 Aug 15;66(16):8109-15. doi: 10.1158/0008-5472.CAN-06-0140. Cancer Res. 2006. PMID: 16912188

9

BRCA1 dysfunction in sporadic basal-like breast cancer.

Turner NC, Reis-Filho JS, Russell AM, Springall RJ, Ryder K, Steele D, Savage K, Gillett CE, Schmitt FC, Ashworth A, Tutt AN. Turner NC, et al. Among authors: tutt an. Oncogene. 2007 Mar 29;26(14):2126-32. doi: 10.1038/sj.onc.1210014. Epub 2006 Oct 2. Oncogene. 2007. PMID: 17016441

10

'Triple negative' breast cancer: a new area for phase III breast cancer clinical trials.

Kilburn LS; TNT Trial Management Group. Kilburn LS, et al. Clin Oncol (R Coll Radiol). 2008 Feb;20(1):35-9. doi: 10.1016/j.clon.2007.09.010. Epub 2007 Oct 31. Clin Oncol (R Coll Radiol). 2008. PMID: 17977700 No abstract available.

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