Tyndale RF - Search Results

1

Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age.

Desta Z, Kreutz Y, Nguyen AT, Li L, Skaar T, Kamdem LK, Henry NL, Hayes DF, Storniolo AM, Stearns V, Hoffmann E, Tyndale RF, Flockhart DA. Desta Z, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2011 Nov;90(5):693-700. doi: 10.1038/clpt.2011.174. Epub 2011 Oct 5. Clin Pharmacol Ther. 2011. PMID: 21975350 Free PMC article. Clinical Trial.

2

Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation.

Tyndale RF, Bhave SV, Hoffmann E, Hoffmann PL, Tabakoff B, Tobin AJ, Olsen RW. Tyndale RF, et al. J Pharmacol Exp Ther. 1997 Oct;283(1):350-7. J Pharmacol Exp Ther. 1997. PMID: 9336343

3

Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment.

Miksys S, Hoffmann E, Tyndale RF. Miksys S, et al. Among authors: tyndale rf. Biochem Pharmacol. 2000 Jun 15;59(12):1501-11. doi: 10.1016/s0006-2952(00)00281-1. Biochem Pharmacol. 2000. PMID: 10799646

4

Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking.

Rao Y, Hoffmann E, Zia M, Bodin L, Zeman M, Sellers EM, Tyndale RF. Rao Y, et al. Among authors: tyndale rf. Mol Pharmacol. 2000 Oct;58(4):747-55. doi: 10.1124/mol.58.4.747. Mol Pharmacol. 2000. PMID: 10999944

5

An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles.

Xu C, Rao YS, Xu B, Hoffmann E, Jones J, Sellers EM, Tyndale RF. Xu C, et al. Among authors: tyndale rf. Biochem Biophys Res Commun. 2002 Jan 11;290(1):318-24. doi: 10.1006/bbrc.2001.6209. Biochem Biophys Res Commun. 2002. PMID: 11779172

6

Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.

Schoedel KA, Hoffmann EB, Rao Y, Sellers EM, Tyndale RF. Schoedel KA, et al. Among authors: tyndale rf. Pharmacogenetics. 2004 Sep;14(9):615-26. doi: 10.1097/00008571-200409000-00006. Pharmacogenetics. 2004. PMID: 15475735

7

Implications of CYP2A6 genetic variation for smoking behaviors and nicotine dependence.

Malaiyandi V, Sellers EM, Tyndale RF. Malaiyandi V, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2005 Mar;77(3):145-58. doi: 10.1016/j.clpt.2004.10.011. Clin Pharmacol Ther. 2005. PMID: 15735609 Review.

8

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

Benowitz NL, Swan GE, Jacob P 3rd, Lessov-Schlaggar CN, Tyndale RF. Benowitz NL, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2006 Nov;80(5):457-67. doi: 10.1016/j.clpt.2006.08.011. Clin Pharmacol Ther. 2006. PMID: 17112802 Clinical Trial.

9

CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial.

Lee AM, Jepson C, Hoffmann E, Epstein L, Hawk LW, Lerman C, Tyndale RF. Lee AM, et al. Among authors: tyndale rf. Biol Psychiatry. 2007 Sep 15;62(6):635-41. doi: 10.1016/j.biopsych.2006.10.005. Epub 2007 Jan 16. Biol Psychiatry. 2007. PMID: 17223085 Clinical Trial.

10

The pharmacogenetics research network: from SNP discovery to clinical drug response.

Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.

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