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The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins.
Belal C, Ameli NJ, El Kommos A, Bezalel S, Al'Khafaji AM, Mughal MR, Mattson MP, Kyriazis GA, Tyrberg B, Chan SL. Belal C, et al. Among authors: tyrberg b. Hum Mol Genet. 2012 Mar 1;21(5):963-77. doi: 10.1093/hmg/ddr502. Epub 2011 Nov 1. Hum Mol Genet. 2012. PMID: 22045699 Free PMC article.
Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis.
Ghiasi SM, Dahllöf MS, Osmai Y, Osmai M, Jakobsen KK, Aivazidis A, Tyrberg B, Perruzza L, Prause MCB, Christensen DP, Fog-Tonnesen M, Lundh M, Grassi F, Chatenoud L, Mandrup-Poulsen T. Ghiasi SM, et al. Among authors: tyrberg b. Mol Cell Endocrinol. 2018 Dec 15;478:106-114. doi: 10.1016/j.mce.2018.08.001. Epub 2018 Aug 16. Mol Cell Endocrinol. 2018. PMID: 30121202
The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets.
Khilji MS, Bresson SE, Verstappen D, Pihl C, Andersen PAK, Agergaard JB, Dahlby T, Bryde TH, Klindt K, Nielsen CK, Walentinsson A, Zivkovic D, Bousquet MP, Tyrberg B, Richardson SJ, Morgan NG, Mandrup-Poulsen T, Marzec MT. Khilji MS, et al. Among authors: tyrberg b. Am J Physiol Endocrinol Metab. 2020 Jun 1;318(6):E892-E900. doi: 10.1152/ajpendo.00372.2019. Epub 2020 Apr 7. Am J Physiol Endocrinol Metab. 2020. PMID: 32255680 Free article.
43 results