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2007 1
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2019 8
2020 6
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2022 7
2023 14
2024 1

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45 results

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Page 1
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.
Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Ordulu Z, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Mahamdeh MS, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Oliva E, Rueda BR, Soberman RJ, Bardeesy N, Liau BB, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L. Zhang J, et al. Among authors: yang ty. Cell. 2023 May 25;186(11):2361-2379.e25. doi: 10.1016/j.cell.2023.04.026. Epub 2023 May 15. Cell. 2023. PMID: 37192619
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Weiss-Sadan T, Ge M, Hayashi M, Gohar M, Yao CH, de Groot A, Harry S, Carlin A, Fischer H, Shi L, Wei TY, Adelmann CH, Wolf K, Vornbäumen T, Dürr BR, Takahashi M, Richter M, Zhang J, Yang TY, Vijay V, Fisher DE, Hata AN, Haigis MC, Mostoslavsky R, Bardeesy N, Papagiannakopoulos T, Bar-Peled L. Weiss-Sadan T, et al. Among authors: yang ty. Cell Metab. 2023 Mar 7;35(3):487-503.e7. doi: 10.1016/j.cmet.2023.01.012. Epub 2023 Feb 24. Cell Metab. 2023. PMID: 36841242 Free PMC article.
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Weiss-Sadan T, Ge M, Hayashi M, Gohar M, Yao CH, de Groot A, Harry S, Carlin A, Fischer H, Shi L, Wei TY, Adelmann CH, Wolf K, Vornbäumen T, Dürr BR, Takahashi M, Richter M, Zhang J, Yang TY, Vijay V, Fisher DE, Hata AN, Haigis MC, Mostoslavsky R, Bardeesy N, Papagiannakopoulos T, Bar-Peled L. Weiss-Sadan T, et al. Among authors: yang ty. Cell Metab. 2023 Apr 4;35(4):722. doi: 10.1016/j.cmet.2023.03.011. Cell Metab. 2023. PMID: 37019082 Free PMC article. No abstract available.
Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome.
Edwinson AL, Yang L, Peters S, Hanning N, Jeraldo P, Jagtap P, Simpson JB, Yang TY, Kumar P, Mehta S, Nair A, Breen-Lyles M, Chikkamenahalli L, Graham RP, De Winter B, Patel R, Dasari S, Kashyap P, Griffin T, Chen J, Farrugia G, Redinbo MR, Grover M. Edwinson AL, et al. Among authors: yang ty. Nat Microbiol. 2022 May;7(5):680-694. doi: 10.1038/s41564-022-01103-1. Epub 2022 Apr 28. Nat Microbiol. 2022. PMID: 35484230 Free PMC article.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Takahashi M, Chong HB, Zhang S, Lazarov MJ, Harry S, Maynard M, White R, Murrey HE, Hilbert B, Neil JR, Gohar M, Ge M, Zhang J, Durr BR, Kryukov G, Tsou CC, Brooijmans N, Alghali ASO, Rubio K, Vilanueva A, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Assaad J, Makram F, Rachman I, Khandelwal N, Tien PC, Popoola G, Chen N, Vordermark K, Richter M, Patel H, Yang TY, Griesshaber H, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Fisher DE, Maheswaran S, Haber DA, Boland G, Sade-Feldman M, Jenkins R, Hata A, Bardeesy N, Suva ML, Martin B, Liau B, Ott C, Rivera MN, Lawrence MS, Bar-Peled L. Takahashi M, et al. Among authors: yang ty. bioRxiv [Preprint]. 2023 Oct 23:2023.10.20.563287. doi: 10.1101/2023.10.20.563287. bioRxiv. 2023. PMID: 37961514 Free PMC article. Updated. Preprint.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Takahashi M, Chong HB, Zhang S, Yang TY, Lazarov MJ, Harry S, Maynard M, Hilbert B, White RD, Murrey HE, Tsou CC, Vordermark K, Assaad J, Gohar M, Dürr BR, Richter M, Patel H, Kryukov G, Brooijmans N, Alghali ASO, Rubio K, Villanueva A, Zhang J, Ge M, Makram F, Griesshaber H, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Popoola G, Rachmin I, Khandelwal N, Neil JR, Tien PC, Chen N, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Kastanos J, Oh E, Fisher DE, Maheswaran S, Haber DA, Boland GM, Sade-Feldman M, Jenkins RW, Hata AN, Bardeesy NM, Suvà ML, Martin BR, Liau BB, Ott CJ, Rivera MN, Lawrence MS, Bar-Peled L. Takahashi M, et al. Among authors: yang ty. Cell. 2024 Apr 17:S0092-8674(24)00318-0. doi: 10.1016/j.cell.2024.03.027. Online ahead of print. Cell. 2024. PMID: 38653237
Assays for tyrosine phosphorylation in human cells.
Kruk M, Widstrom N, Jena S, Wolter NL, Blankenhorn JF, Abdalla I, Yang TY, Parker LL. Kruk M, et al. Among authors: yang ty. Methods Enzymol. 2019;626:375-406. doi: 10.1016/bs.mie.2019.06.026. Epub 2019 Jul 24. Methods Enzymol. 2019. PMID: 31606083 Free PMC article.
45 results