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Year Number of Results
2020 5
2021 2
2022 4
2023 4
2024 3

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18 results

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Page 1
RNA language models predict mutations that improve RNA function.
Shulgina Y, Trinidad MI, Langeberg CJ, Nisonoff H, Chithrananda S, Skopintsev P, Nissley AJ, Patel J, Boger RS, Shi H, Yoon PH, Doherty EE, Pande T, Iyer AM, Doudna JA, Cate JHD. Shulgina Y, et al. bioRxiv [Preprint]. 2024 Apr 6:2024.04.05.588317. doi: 10.1101/2024.04.05.588317. bioRxiv. 2024. PMID: 38617247 Free PMC article. Preprint.
Hachiman is a genome integrity sensor.
Tuck OT, Adler BA, Armbruster EG, Lahiri A, Hu JJ, Zhou J, Pogliano J, Doudna JA. Tuck OT, et al. bioRxiv [Preprint]. 2024 Feb 29:2024.02.29.582594. doi: 10.1101/2024.02.29.582594. bioRxiv. 2024. PMID: 38464307 Free PMC article. Preprint.
Targeted nonviral delivery of genome editors in vivo.
Tsuchida CA, Wasko KM, Hamilton JR, Doudna JA. Tsuchida CA, et al. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307796121. doi: 10.1073/pnas.2307796121. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437567 Free PMC article. Review.
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes.
Yoon PH, Skopintsev P, Shi H, Chen L, Adler BA, Al-Shimary M, Craig RJ, Loi KJ, DeTurk EC, Li Z, Amerasekera J, Trinidad M, Nisonoff H, Chen K, Lahiri A, Boger R, Jacobsen S, Banfield JF, Doudna JA. Yoon PH, et al. Nucleic Acids Res. 2023 Dec 11;51(22):12414-12427. doi: 10.1093/nar/gkad1053. Nucleic Acids Res. 2023. PMID: 37971304 Free PMC article.
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.
Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Hofman L, Satpathy AT, Stadtmauer EA, Cate JHD, Eyquem J, Fraietta JA, June CH, Chang HY, Ye CJ, Doudna JA. Tsuchida CA, et al. Cell. 2023 Oct 12;186(21):4567-4582.e20. doi: 10.1016/j.cell.2023.08.041. Epub 2023 Oct 3. Cell. 2023. PMID: 37794590 Free PMC article.
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.
Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Satpathy AT, Stadtmauer EA, Cate JHD, Eyquem J, Fraietta JA, June CH, Chang HY, Ye CJ, Doudna JA. Tsuchida CA, et al. bioRxiv [Preprint]. 2023 Mar 22:2023.03.22.533709. doi: 10.1101/2023.03.22.533709. bioRxiv. 2023. PMID: 36993359 Free PMC article. Updated. Preprint.
Precise transcript targeting by CRISPR-Csm complexes.
Colognori D, Trinidad M, Doudna JA. Colognori D, et al. Nat Biotechnol. 2023 Sep;41(9):1256-1264. doi: 10.1038/s41587-022-01649-9. Epub 2023 Jan 23. Nat Biotechnol. 2023. PMID: 36690762 Free PMC article.
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
Crystal structure of an RNA/DNA strand exchange junction.
Cofsky JC, Knott GJ, Gee CL, Doudna JA. Cofsky JC, et al. PLoS One. 2022 Apr 18;17(4):e0263547. doi: 10.1371/journal.pone.0263547. eCollection 2022. PLoS One. 2022. PMID: 35436289 Free PMC article.
18 results