Uger RA - Search Results

1

Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy.

Diamanti P, Cox CV, Ede BC, Uger RA, Moppett JP, Blair A. Diamanti P, et al. Among authors: uger ra. Blood Adv. 2021 Sep 28;5(18):3694-3708. doi: 10.1182/bloodadvances.2020003534. Blood Adv. 2021. PMID: 34470052 Free PMC article.

2

Targeting CD47 in Sézary syndrome with SIRPαFc.

Johnson LDS, Banerjee S, Kruglov O, Viller NN, Horwitz SM, Lesokhin A, Zain J, Querfeld C, Chen R, Okada C, Sawas A, O'Connor OA, Sievers EL, Shou Y, Uger RA, Wong M, Akilov OE. Johnson LDS, et al. Among authors: uger ra. Blood Adv. 2019 Apr 9;3(7):1145-1153. doi: 10.1182/bloodadvances.2018030577. Blood Adv. 2019. PMID: 30962222 Free PMC article. Clinical Trial.

3

Use of an anti-CD200-blocking antibody improves immune responses to AML in vitro and in vivo.

Rastogi N, Baker S, Man S, Uger RA, Wong M, Coles SJ, Hodges M, Gilkes AF, Knapper S, Darley RL, Tonks A. Rastogi N, et al. Among authors: uger ra. Br J Haematol. 2021 Apr;193(1):155-159. doi: 10.1111/bjh.17125. Epub 2020 Sep 30. Br J Haematol. 2021. PMID: 32996123 Free PMC article.

4

The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides.

Kruglov O, Johnson LDS, Minic A, Jordan K, Uger RA, Wong M, Sievers EL, Shou Y, Akilov OE. Kruglov O, et al. Among authors: uger ra. Cancer Immunol Immunother. 2022 Apr;71(4):919-932. doi: 10.1007/s00262-021-03051-x. Epub 2021 Sep 14. Cancer Immunol Immunother. 2022. PMID: 34519839 Free PMC article.

5

Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade.

Pallasch CP, Ulbrich S, Brinker R, Hallek M, Uger RA, Wendtner CM. Pallasch CP, et al. Among authors: uger ra. Leuk Res. 2009 Mar;33(3):460-4. doi: 10.1016/j.leukres.2008.08.021. Epub 2008 Oct 5. Leuk Res. 2009. PMID: 18838168

6

TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets.

Lin GHY, Chai V, Lee V, Dodge K, Truong T, Wong M, Johnson LD, Linderoth E, Pang X, Winston J, Petrova PS, Uger RA, Viller NN. Lin GHY, et al. Among authors: uger ra. PLoS One. 2017 Oct 30;12(10):e0187262. doi: 10.1371/journal.pone.0187262. eCollection 2017. PLoS One. 2017. PMID: 29084248 Free PMC article.

7

SIRPαFc treatment targets human acute myeloid leukemia stem cells.

Galkin O, McLeod J, Kennedy JA, Jin L, Mbong N, Wong M, Uger RA, Minden MD, Danska JS, Wang JCY. Galkin O, et al. Among authors: uger ra. Haematologica. 2021 Jan 1;106(1):279-283. doi: 10.3324/haematol.2019.245167. Haematologica. 2021. PMID: 32054659 Free PMC article. No abstract available.

8

Targeting CD47-SIRPa axis shows potent preclinical anti-tumor activity as monotherapy and synergizes with PARP inhibition.

Al-Sudani H, Ni Y, Jones P, Karakilic H, Cui L, Johnson LDS, Rose PG, Olawaiye A, Edwards RP, Uger RA, Lin GHY, Mahdi H. Al-Sudani H, et al. Among authors: uger ra. NPJ Precis Oncol. 2023 Jul 19;7(1):69. doi: 10.1038/s41698-023-00418-4. NPJ Precis Oncol. 2023. PMID: 37468567 Free PMC article.

9

Clinical Response to Anti-CD47 Immunotherapy Is Associated with Rapid Reduction of Exhausted Bystander CD4⁺ BTLA⁺ T Cells in Tumor Microenvironment of Mycosis Fungoides.

Jiang TT, Kruglov O, Lin GHY, Minic A, Jordan K, Uger RA, Wong M, Shou Y, Akilov OE. Jiang TT, et al. Among authors: uger ra. Cancers (Basel). 2021 Nov 28;13(23):5982. doi: 10.3390/cancers13235982. Cancers (Basel). 2021. PMID: 34885092 Free PMC article.

10

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.

Petrova PS, Viller NN, Wong M, Pang X, Lin GH, Dodge K, Chai V, Chen H, Lee V, House V, Vigo NT, Jin D, Mutukura T, Charbonneau M, Truong T, Viau S, Johnson LD, Linderoth E, Sievers EL, Maleki Vareki S, Figueredo R, Pampillo M, Koropatnick J, Trudel S, Mbong N, Jin L, Wang JC, Uger RA. Petrova PS, et al. Among authors: uger ra. Clin Cancer Res. 2017 Feb 15;23(4):1068-1079. doi: 10.1158/1078-0432.CCR-16-1700. Epub 2016 Nov 17. Clin Cancer Res. 2017. PMID: 27856600

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