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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities.
Zhang Y, Remillard D, Onubogu U, Karakyriakou B, Asiaban JN, Ramos AR, Bowland K, Bishop TR, Barta PA, Nance S, Durbin AD, Ott CJ, Janiszewska M, Cravatt BF, Erb MA. Zhang Y, et al. Among authors: onubogu u. Nat Struct Mol Biol. 2023 Aug;30(8):1160-1171. doi: 10.1038/s41594-023-01041-4. Epub 2023 Jul 24. Nat Struct Mol Biol. 2023. PMID: 37488358 Free PMC article.
Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma.
Walentynowicz KA, Engelhardt D, Cristea S, Yadav S, Onubogu U, Salatino R, Maerken M, Vincentelli C, Jhaveri A, Geisberg J, McDonald TO, Michor F, Janiszewska M. Walentynowicz KA, et al. Among authors: onubogu u. Cell Rep. 2023 Mar 28;42(3):112235. doi: 10.1016/j.celrep.2023.112235. Epub 2023 Mar 14. Cell Rep. 2023. PMID: 36920905 Free PMC article.