Unzai S - Search Results

1

EGFR extracellular domain III expressed in Escherichia coli with SEP tag shows improved biophysical and functional properties and generate anti-sera inhibiting cancer cell growth.

Brindha S, Kibria MG, Saotome T, Unzai S, Kuroda Y. Brindha S, et al. Among authors: unzai s. Biochem Biophys Res Commun. 2021 May 28;555:121-127. doi: 10.1016/j.bbrc.2021.03.102. Epub 2021 Apr 1. Biochem Biophys Res Commun. 2021. PMID: 33813270

2

Thermodynamic Analysis of Point Mutations Inhibiting High-Temperature Reversible Oligomerization of PDZ3.

Saotome T, Mezaki T, Brindha S, Unzai S, Martinez JC, Kidokoro SI, Kuroda Y. Saotome T, et al. Among authors: unzai s. Biophys J. 2020 Oct 6;119(7):1391-1401. doi: 10.1016/j.bpj.2020.08.023. Epub 2020 Aug 28. Biophys J. 2020. PMID: 32961107 Free PMC article.

3

Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR.

Wu N, Kobayashi N, Tsuda K, Unzai S, Saotome T, Kuroda Y, Yamazaki T. Wu N, et al. Among authors: unzai s. Sci Rep. 2020 Nov 18;10(1):20069. doi: 10.1038/s41598-020-76486-4. Sci Rep. 2020. PMID: 33208800 Free PMC article.

4

Blocking PSD95-PDZ3's amyloidogenesis through point mutations that inhibit high-temperature reversible oligomerization (RO).

Saotome T, Onchaiya S, Brindha S, Mezaki T, Unzai S, Noguchi K, Martinez JC, Kidokoro SI, Kuroda Y. Saotome T, et al. Among authors: unzai s. FEBS J. 2022 Jun;289(11):3205-3216. doi: 10.1111/febs.16339. Epub 2022 Jan 18. FEBS J. 2022. PMID: 34967499 Free article.

5

Nanometer-Sized Aggregates Generated Using Short Solubility Controlling Peptide Tags Do Increase the In Vivo Immunogenicity of a Nonimmunogenic Protein.

Rahman N, Islam MM, Unzai S, Miura S, Kuroda Y. Rahman N, et al. Among authors: unzai s. Mol Pharm. 2020 May 4;17(5):1629-1637. doi: 10.1021/acs.molpharmaceut.0c00071. Epub 2020 Apr 21. Mol Pharm. 2020. PMID: 32227965

6

Reversible Oligomerization and Reverse Hydrophobic Effect Induced by Isoleucine Tags Attached at the C-Terminus of a Simplified BPTI Variant.

Nakamura S, Kibria MG, Unzai S, Kuroda Y, Kidokoro SI. Nakamura S, et al. Among authors: unzai s. Biochemistry. 2020 Oct 6;59(39):3660-3668. doi: 10.1021/acs.biochem.0c00436. Epub 2020 Sep 22. Biochemistry. 2020. PMID: 32924442

7

A systematic mutational analysis identifies a 5-residue proline tag that enhances the in vivo immunogenicity of a non-immunogenic model protein.

Rahman N, Islam MM, Kibria MG, Unzai S, Kuroda Y. Rahman N, et al. Among authors: unzai s. FEBS Open Bio. 2020 Oct;10(10):1947-1956. doi: 10.1002/2211-5463.12941. Epub 2020 Aug 30. FEBS Open Bio. 2020. PMID: 33017095 Free PMC article.

8

The structure and conformational switching of Rap1B.

Noguchi H, Ikegami T, Nagadoi A, Kamatari YO, Park SY, Tame JR, Unzai S. Noguchi H, et al. Among authors: unzai s. Biochem Biophys Res Commun. 2015 Jun 19;462(1):46-51. doi: 10.1016/j.bbrc.2015.04.103. Epub 2015 Apr 29. Biochem Biophys Res Commun. 2015. PMID: 25935485 Free article.

9

Analytical ultracentrifugation in structural biology.

Unzai S. Unzai S. Biophys Rev. 2018 Apr;10(2):229-233. doi: 10.1007/s12551-017-0340-0. Epub 2017 Nov 29. Biophys Rev. 2018. PMID: 29188538 Free PMC article. Review.

10

Oligomerization of Hmo1 mediated by box A is essential for DNA binding in vitro and in vivo.

Kasahara K, Higashino A, Unzai S, Yoshikawa H, Kokubo T. Kasahara K, et al. Among authors: unzai s. Genes Cells. 2016 Dec;21(12):1333-1352. doi: 10.1111/gtc.12449. Epub 2016 Nov 15. Genes Cells. 2016. PMID: 27860073 Free article.

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