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Page 1
The proteomic landscape of genome-wide genetic perturbations.
Messner CB, Demichev V, Muenzner J, Aulakh SK, Barthel N, Röhl A, Herrera-Domínguez L, Egger AS, Kamrad S, Hou J, Tan G, Lemke O, Calvani E, Szyrwiel L, Mülleder M, Lilley KS, Boone C, Kustatscher G, Ralser M. Messner CB, et al. Among authors: demichev v. Cell. 2023 Apr 27;186(9):2018-2034.e21. doi: 10.1016/j.cell.2023.03.026. Epub 2023 Apr 19. Cell. 2023. PMID: 37080200 Free PMC article.
Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg P, Astaburuaga-García R, Bonaguro L, Brumhard S, Michalick L, Lippert LJ, Kostevc T, Gäbel C, Schneider M, Streitz M, Demichev V, Gemünd I, Barone M, Tober-Lau P, Helbig ET, Hillus D, Petrov L, Stein J, Dey HP, Paclik D, Iwert C, Mülleder M, Aulakh SK, Djudjaj S, Bülow RD, Mei HE, Schulz AR, Thiel A, Hippenstiel S, Saliba AE, Eils R, Lehmann I, Mall MA, Stricker S, Röhmel J, Corman VM, Beule D, Wyler E, Landthaler M, Obermayer B, von Stillfried S, Boor P, Demir M, Wesselmann H, Suttorp N, Uhrig A, Müller-Redetzky H, Nattermann J, Kuebler WM, Meisel C, Ralser M, Schultze JL, Aschenbrenner AC, Thibeault C, Kurth F, Sander LE, Blüthgen N, Sawitzki B; PA-COVID-19 Study Group. Georg P, et al. Among authors: demichev v. Cell. 2022 Feb 3;185(3):493-512.e25. doi: 10.1016/j.cell.2021.12.040. Epub 2021 Dec 28. Cell. 2022. PMID: 35032429 Free PMC article.
Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.
Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend S, Jayasree Varma S, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Kaur Aulakh S, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M. Correia-Melo C, et al. Among authors: demichev v. Cell. 2023 Jan 5;186(1):63-79.e21. doi: 10.1016/j.cell.2022.12.007. Cell. 2023. PMID: 36608659 Free article.
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection.
Messner CB, Demichev V, Wendisch D, Michalick L, White M, Freiwald A, Textoris-Taube K, Vernardis SI, Egger AS, Kreidl M, Ludwig D, Kilian C, Agostini F, Zelezniak A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, von Kalle C, Campbell A, Hayward C, Porteous DJ, Marioni RE, Langenberg C, Lilley KS, Kuebler WM, Mülleder M, Drosten C, Suttorp N, Witzenrath M, Kurth F, Sander LE, Ralser M. Messner CB, et al. Among authors: demichev v. Cell Syst. 2020 Jul 22;11(1):11-24.e4. doi: 10.1016/j.cels.2020.05.012. Epub 2020 Jun 2. Cell Syst. 2020. PMID: 32619549 Free PMC article.
Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments.
Gatto L, Aebersold R, Cox J, Demichev V, Derks J, Emmott E, Franks AM, Ivanov AR, Kelly RT, Khoury L, Leduc A, MacCoss MJ, Nemes P, Perlman DH, Petelski AA, Rose CM, Schoof EM, Van Eyk J, Vanderaa C, Yates JR 3rd, Slavov N. Gatto L, et al. Among authors: demichev v. Nat Methods. 2023 Mar;20(3):375-386. doi: 10.1038/s41592-023-01785-3. Epub 2023 Mar 2. Nat Methods. 2023. PMID: 36864200 Free PMC article. Review.
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells.
Talwar D, Miller CG, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, Mikecin Drazic AM, Mayakonda A, Lutsik P, Veith C, Milsom MD, Müller-Decker K, Mülleder M, Ralser M, Dick TP. Talwar D, et al. Among authors: demichev v. Nat Metab. 2023 Apr;5(4):660-676. doi: 10.1038/s42255-023-00781-3. Epub 2023 Apr 6. Nat Metab. 2023. PMID: 37024754 Free PMC article.
Increasing the throughput of sensitive proteomics by plexDIA.
Derks J, Leduc A, Wallmann G, Huffman RG, Willetts M, Khan S, Specht H, Ralser M, Demichev V, Slavov N. Derks J, et al. Among authors: demichev v. Nat Biotechnol. 2023 Jan;41(1):50-59. doi: 10.1038/s41587-022-01389-w. Epub 2022 Jul 14. Nat Biotechnol. 2023. PMID: 35835881 Free PMC article.
35 results