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IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes.
Poholek AC, Jankovic D, Villarino AV, Petermann F, Hettinga A, Shouval DS, Snapper SB, Kaech SM, Brooks SR, Vahedi G, Sher A, Kanno Y, O'Shea JJ. Poholek AC, et al. Among authors: vahedi g. Sci Immunol. 2016 Oct;1(5):eaaf8612. doi: 10.1126/sciimmunol.aaf8612. Epub 2016 Nov 11. Sci Immunol. 2016. PMID: 28713870 Free PMC article.
High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: vahedi g. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
Helper T-cell differentiation and plasticity: insights from epigenetics.
Hirahara K, Vahedi G, Ghoreschi K, Yang XP, Nakayamada S, Kanno Y, O'Shea JJ, Laurence A. Hirahara K, et al. Among authors: vahedi g. Immunology. 2011 Nov;134(3):235-45. doi: 10.1111/j.1365-2567.2011.03483.x. Immunology. 2011. PMID: 21977994 Free PMC article. Review.
Early Th1 cell differentiation is marked by a Tfh cell-like transition.
Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ. Nakayamada S, et al. Among authors: vahedi g. Immunity. 2011 Dec 23;35(6):919-31. doi: 10.1016/j.immuni.2011.11.012. Immunity. 2011. PMID: 22195747 Free PMC article.
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.
Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ. Hirahara K, et al. Among authors: vahedi g. Immunity. 2012 Jun 29;36(6):1017-30. doi: 10.1016/j.immuni.2012.03.024. Epub 2012 Jun 21. Immunity. 2012. PMID: 22726954 Free PMC article.
99 results