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Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.
Kiss GN, Lee SC, Fells JI, Liu J, Valentine WJ, Fujiwara Y, Thompson KE, Yates CR, Sümegi B, Tigyi G. Kiss GN, et al. Among authors: valentine wj. Biochim Biophys Acta. 2013 Jan;1831(1):117-25. doi: 10.1016/j.bbalip.2012.08.020. Biochim Biophys Acta. 2013. PMID: 23127512 Free PMC article.
Lysophospholipid signaling: beyond the EDGs.
Valentine WJ, Fujiwara Y, Tsukahara R, Tigyi G. Valentine WJ, et al. Biochim Biophys Acta. 2008 Mar;1780(3):597-605. doi: 10.1016/j.bbagen.2007.08.008. Epub 2007 Aug 25. Biochim Biophys Acta. 2008. PMID: 17931789 Free PMC article.
The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.
Deng W, Shuyu E, Tsukahara R, Valentine WJ, Durgam G, Gududuru V, Balazs L, Manickam V, Arsura M, VanMiddlesworth L, Johnson LR, Parrill AL, Miller DD, Tigyi G. Deng W, et al. Among authors: valentine wj. Gastroenterology. 2007 May;132(5):1834-51. doi: 10.1053/j.gastro.2007.03.038. Epub 2007 Mar 24. Gastroenterology. 2007. PMID: 17484878 Free PMC article.
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity.
Valentine WJ, Kiss GN, Liu J, E S, Gotoh M, Murakami-Murofushi K, Pham TC, Baker DL, Parrill AL, Lu X, Sun C, Bittman R, Pyne NJ, Tigyi G. Valentine WJ, et al. Cell Signal. 2010 Oct;22(10):1543-53. doi: 10.1016/j.cellsig.2010.05.023. Epub 2010 Jun 4. Cell Signal. 2010. PMID: 20566326 Free PMC article.
Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma.
Tsukahara T, Tsukahara R, Yasuda S, Makarova N, Valentine WJ, Allison P, Yuan H, Baker DL, Li Z, Bittman R, Parrill A, Tigyi G. Tsukahara T, et al. Among authors: valentine wj. J Biol Chem. 2006 Feb 10;281(6):3398-407. doi: 10.1074/jbc.M510843200. Epub 2005 Dec 1. J Biol Chem. 2006. PMID: 16321982 Free article.
169 results