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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.
Van Gorp H, Saavedra PH, de Vasconcelos NM, Van Opdenbosch N, Vande Walle L, Matusiak M, Prencipe G, Insalaco A, Van Hauwermeiren F, Demon D, Bogaert DJ, Dullaers M, De Baere E, Hochepied T, Dehoorne J, Vermaelen KY, Haerynck F, De Benedetti F, Lamkanfi M. Van Gorp H, et al. Among authors: van hauwermeiren f, van opdenbosch n. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14384-14389. doi: 10.1073/pnas.1613156113. Epub 2016 Nov 22. Proc Natl Acad Sci U S A. 2016. PMID: 27911804 Free PMC article.
NOD-like receptors interfacing the immune and reproductive systems.
Van Gorp H, Kuchmiy A, Van Hauwermeiren F, Lamkanfi M. Van Gorp H, et al. Among authors: van hauwermeiren f. FEBS J. 2014 Oct;281(20):4568-82. doi: 10.1111/febs.13014. Epub 2014 Sep 30. FEBS J. 2014. PMID: 25154302 Free article. Review.
Protective and detrimental roles of inflammasomes in disease.
Saavedra PH, Demon D, Van Gorp H, Lamkanfi M. Saavedra PH, et al. Among authors: van gorp h. Semin Immunopathol. 2015 Jul;37(4):313-22. doi: 10.1007/s00281-015-0485-5. Epub 2015 Apr 21. Semin Immunopathol. 2015. PMID: 25895577 Review.
Does caspase-12 suppress inflammasome activation?
Vande Walle L, Jiménez Fernández D, Demon D, Van Laethem N, Van Hauwermeiren F, Van Gorp H, Van Opdenbosch N, Kayagaki N, Lamkanfi M. Vande Walle L, et al. Among authors: van laethem n, van hauwermeiren f, van opdenbosch n, van gorp h. Nature. 2016 Jun 2;534(7605):E1-4. doi: 10.1038/nature17649. Nature. 2016. PMID: 27251234 No abstract available.
Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.
Van Opdenbosch N, Van Gorp H, Verdonckt M, Saavedra PHV, de Vasconcelos NM, Gonçalves A, Vande Walle L, Demon D, Matusiak M, Van Hauwermeiren F, D'Hont J, Hochepied T, Krautwald S, Kanneganti TD, Lamkanfi M. Van Opdenbosch N, et al. Among authors: van hauwermeiren f, van gorp h. Cell Rep. 2017 Dec 19;21(12):3427-3444. doi: 10.1016/j.celrep.2017.11.088. Cell Rep. 2017. PMID: 29262324 Free PMC article.
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation.
Tavernier SJ, Athanasopoulos V, Verloo P, Behrens G, Staal J, Bogaert DJ, Naesens L, De Bruyne M, Van Gassen S, Parthoens E, Ellyard J, Cappello J, Morris LX, Van Gorp H, Van Isterdael G, Saeys Y, Lamkanfi M, Schelstraete P, Dehoorne J, Bordon V, Van Coster R, Lambrecht BN, Menten B, Beyaert R, Vinuesa CG, Heissmeyer V, Dullaers M, Haerynck F. Tavernier SJ, et al. Among authors: van isterdael g, van coster r, van gassen s, van gorp h. Nat Commun. 2019 Oct 21;10(1):4779. doi: 10.1038/s41467-019-12704-6. Nat Commun. 2019. PMID: 31636267 Free PMC article.
49 results