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MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells.
Mukherjee N, Skees J, Todd KJ, West DA, Lambert KA, Robinson WA, Amato CM, Couts KL, Van Gulick R, MacBeth M, Nassar K, Tan AC, Zhai Z, Fujita M, Bagby SM, Dart CR, Lambert JR, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: van gulick r. Cell Death Dis. 2020 Jun 8;11(6):443. doi: 10.1038/s41419-020-2646-2. Cell Death Dis. 2020. PMID: 32513939 Free PMC article.
BRAF fusions identified in melanomas have variable treatment responses and phenotypes.
Turner JA, Bemis JGT, Bagby SM, Capasso A, Yacob BW, Chimed TS, Van Gulick R, Lee H, Tobin R, Tentler JJ, Pitts T, McCarter M, Robinson WA, Couts KL. Turner JA, et al. Among authors: van gulick r. Oncogene. 2019 Feb;38(8):1296-1308. doi: 10.1038/s41388-018-0514-7. Epub 2018 Sep 25. Oncogene. 2019. PMID: 30254212
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity.
Newell F, Wilmott JS, Johansson PA, Nones K, Addala V, Mukhopadhyay P, Broit N, Amato CM, Van Gulick R, Kazakoff SH, Patch AM, Koufariotis LT, Lakis V, Leonard C, Wood S, Holmes O, Xu Q, Lewis K, Medina T, Gonzalez R, Saw RPM, Spillane AJ, Stretch JR, Rawson RV, Ferguson PM, Dodds TJ, Thompson JF, Long GV, Levesque MP, Robinson WA, Pearson JV, Mann GJ, Scolyer RA, Waddell N, Hayward NK. Newell F, et al. Among authors: van gulick r. Nat Commun. 2020 Oct 16;11(1):5259. doi: 10.1038/s41467-020-18988-3. Nat Commun. 2020. PMID: 33067454 Free PMC article.
Melanoma Metastases to the Adrenal Gland Are Highly Resistant to Immune Checkpoint Inhibitors.
Borgers JSW, Tobin RP, Torphy RJ, Vorwald VM, Van Gulick RJ, Amato CM, Cogswell DT, Chimed TS, Couts KL, Van Bokhoven A, Raeburn CD, Lewis KD, Wisell J, McCarter MD, Mushtaq RR, Robinson WA. Borgers JSW, et al. Among authors: van gulick rj. J Natl Compr Canc Netw. 2021 Aug 4:jnccn20283. doi: 10.6004/jnccn.2020.7800. Online ahead of print. J Natl Compr Canc Netw. 2021. PMID: 34348236
A Novel Regimen for Treating Melanoma: MCL1 Inhibitors and Azacitidine.
Dart CR, Mukherjee N, Amato CM, Goulding A, MacBeth M, Van Gulick R, Couts KL, Lambert JR, Norris DA, Robinson WA, Shellman YG. Dart CR, et al. Among authors: van gulick r. Pharmaceuticals (Basel). 2021 Jul 30;14(8):749. doi: 10.3390/ph14080749. Pharmaceuticals (Basel). 2021. PMID: 34451846 Free PMC article.
Circulating CD8+ mucosal-associated invariant T cells correlate with improved treatment responses and overall survival in anti-PD-1-treated melanoma patients.
Vorwald VM, Davis DM, Van Gulick RJ, Torphy RJ, Borgers JS, Klarquist J, Couts KL, Amato CM, Cogswell DT, Fujita M, Castleman MJ, Davis T, Lozupone C, Medina TM, Robinson WA, Gapin L, McCarter MD, Tobin RP. Vorwald VM, et al. Among authors: van gulick rj. Clin Transl Immunology. 2022 Jan 10;11(1):e1367. doi: 10.1002/cti2.1367. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35028137 Free PMC article.
BRAF Modulates Lipid Use and Accumulation.
Turner JA, Paton EL, Van Gulick R, Stefanoni D, Cendali F, Reisz J, Tobin RP, McCarter M, D'Alessandro A, Torres RM, Robinson WA, Couts KL, Schlaepfer IR. Turner JA, et al. Among authors: van gulick r. Cancers (Basel). 2022 Apr 23;14(9):2110. doi: 10.3390/cancers14092110. Cancers (Basel). 2022. PMID: 35565240 Free PMC article.
Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma.
Tobin RP, Cogswell DT, Cates VM, Davis DM, Borgers JSW, Van Gulick RJ, Katsnelson E, Couts KL, Jordan KR, Gao D, Davila E, Medina TM, Lewis KD, Gonzalez R, McFarland RW, Robinson WA, McCarter MD. Tobin RP, et al. Among authors: van gulick rj. Clin Cancer Res. 2023 Apr 3;29(7):1209-1219. doi: 10.1158/1078-0432.CCR-22-2495. Clin Cancer Res. 2023. PMID: 36378549 Free PMC article.
13 results