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A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.
De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guérin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W. De Groote P, et al. Among authors: van imschoot g. Cell Death Differ. 2015 Jun;22(6):1012-24. doi: 10.1038/cdd.2014.191. Epub 2014 Nov 28. Cell Death Differ. 2015. PMID: 25430793 Free PMC article.
TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C. Steeland S, et al. Among authors: van imschoot g, van ryckeghem s. Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y. Sci Rep. 2017. PMID: 29057962 Free PMC article.
Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.
Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE. Steeland S, et al. Among authors: van cauwenberghe c, van imschoot g, van wonterghem e. EMBO Mol Med. 2018 Apr;10(4):e8300. doi: 10.15252/emmm.201708300. EMBO Mol Med. 2018. PMID: 29472246 Free PMC article.
Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.
Xie J, Gorlé N, Vandendriessche C, Van Imschoot G, Van Wonterghem E, Van Cauwenberghe C, Parthoens E, Van Hamme E, Lippens S, Van Hoecke L, Vandenbroucke RE. Xie J, et al. Among authors: van cauwenberghe c, van imschoot g, van wonterghem e, van hamme e, van hoecke l. Acta Neuropathol Commun. 2021 Oct 7;9(1):163. doi: 10.1186/s40478-021-01253-z. Acta Neuropathol Commun. 2021. PMID: 34620254 Free PMC article.
28 results