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Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity.
Huang FC, Galemmo RA Jr, Poli GB, Learn KS, Morrissette MM, Johnson WH Jr, Dankulich WP, Campbell HF, Carnathan GW, VanInwegen RG. Huang FC, et al. J Med Chem. 1991 May;34(5):1704-7. doi: 10.1021/jm00109a025. J Med Chem. 1991. PMID: 1851845
The inhibition of 5-lipoxygenase by RG 6866.
Carnathan GW, Sweeney DM, Travis JJ, Gordon RJ, Sutherland CA, Jariwala N, Clearfield M, O'Rourke S, Huang FC, Van Inwegen RG. Carnathan GW, et al. Among authors: van inwegen rg. Agents Actions. 1989 Nov;28(3-4):204-11. doi: 10.1007/BF01967402. Agents Actions. 1989. PMID: 2596372
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