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Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.
Cauwels A, Van Lint S, Paul F, Garcin G, De Koker S, Van Parys A, Wueest T, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, Rogge E, Verhee A, Vandekerckhove B, Kley N, Uzé G, Tavernier J. Cauwels A, et al. Among authors: van lint s, van parys a, van der heyden j. Cancer Res. 2018 Jan 15;78(2):463-474. doi: 10.1158/0008-5472.CAN-17-1980. Epub 2017 Nov 29. Cancer Res. 2018. PMID: 29187401
High efficiency cell-specific targeting of cytokine activity.
Garcin G, Paul F, Staufenbiel M, Bordat Y, Van der Heyden J, Wilmes S, Cartron G, Apparailly F, De Koker S, Piehler J, Tavernier J, Uzé G. Garcin G, et al. Among authors: van der heyden j. Nat Commun. 2014;5:3016. doi: 10.1038/ncomms4016. Nat Commun. 2014. PMID: 24398568 Free article.
A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment.
Cauwels A, Van Lint S, Garcin G, Bultinck J, Paul F, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, De Cauwer L, Rogge E, Verhee A, Uzé G, Tavernier J. Cauwels A, et al. Among authors: van lint s, van der heyden j. Oncoimmunology. 2017 Nov 27;7(3):e1398876. doi: 10.1080/2162402X.2017.1398876. eCollection 2018. Oncoimmunology. 2017. PMID: 29399401 Free PMC article.
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly.
De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, Vandekerckhove B. De Munter S, et al. Among authors: van parys a, van der heyden j. Int J Mol Sci. 2020 Jan 30;21(3):883. doi: 10.3390/ijms21030883. Int J Mol Sci. 2020. PMID: 32019116 Free PMC article.
Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level.
Zabeau L, Jensen CJ, Seeuws S, Venken K, Verhee A, Catteeuw D, van Loo G, Chen H, Walder K, Hollis J, Foote S, Morris MJ, Van der Heyden J, Peelman F, Oldfield BJ, Rubio JP, Elewaut D, Tavernier J. Zabeau L, et al. Among authors: van loo g, van der heyden j. Cell Mol Life Sci. 2015 Feb;72(3):629-644. doi: 10.1007/s00018-014-1697-x. Epub 2014 Aug 7. Cell Mol Life Sci. 2015. PMID: 25098352 Free PMC article.
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis.
Lavens D, Peelman F, Van der Heyden J, Uyttendaele I, Catteeuw D, Verhee A, Van Schoubroeck B, Kurth J, Hallenberger S, Clayton R, Tavernier J. Lavens D, et al. Among authors: van schoubroeck b, van der heyden j. Nucleic Acids Res. 2010 Apr;38(6):1902-12. doi: 10.1093/nar/gkp1154. Epub 2009 Dec 16. Nucleic Acids Res. 2010. PMID: 20015971 Free PMC article.
The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein.
Van Ostade X, Van der Heyden J, Verhee A, Vandekerckhove J, Tavernier J. Van Ostade X, et al. Among authors: van der heyden j. Eur J Biochem. 1999 Feb;259(3):954-60. doi: 10.1046/j.1432-1327.1999.00148.x. Eur J Biochem. 1999. PMID: 10092887 Free article.
However, analysis of the effect of this mutant IL-5 on COS-1 cells transfected with both receptor subunits, did not show reduced interaction with the beta c subunit [Tavernier, J., Tuypens, T., Verhee, A., Plaetinck, G., Devos, R., Van der Heyden, J …
However, analysis of the effect of this mutant IL-5 on COS-1 cells transfected with both receptor subunits, did not show reduced interaction …
315 results