Vanderwall DE - Search Results

1

Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

Xu RX, Rocque WJ, Lambert MH, Vanderwall DE, Luther MA, Nolte RT. Xu RX, et al. Among authors: vanderwall de. J Mol Biol. 2004 Mar 19;337(2):355-65. doi: 10.1016/j.jmb.2004.01.040. J Mol Biol. 2004. PMID: 15003452

2

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.

Xu RX, Hassell AM, Vanderwall D, Lambert MH, Holmes WD, Luther MA, Rocque WJ, Milburn MV, Zhao Y, Ke H, Nolte RT. Xu RX, et al. Science. 2000 Jun 9;288(5472):1822-5. doi: 10.1126/science.288.5472.1822. Science. 2000. PMID: 10846163

3

Correlation between in vitro peptide binding profiles and cellular activities for estrogen receptor-modulating compounds.

Iannone MA, Simmons CA, Kadwell SH, Svoboda DL, Vanderwall DE, Deng SJ, Consler TG, Shearin J, Gray JG, Pearce KH. Iannone MA, et al. Among authors: vanderwall de. Mol Endocrinol. 2004 May;18(5):1064-81. doi: 10.1210/me.2003-0432. Epub 2004 Feb 19. Mol Endocrinol. 2004. PMID: 14976226

4

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases.

Wood ER, Shewchuk LM, Ellis B, Brignola P, Brashear RL, Caferro TR, Dickerson SH, Dickson HD, Donaldson KH, Gaul M, Griffin RJ, Hassell AM, Keith B, Mullin R, Petrov KG, Reno MJ, Rusnak DW, Tadepalli SM, Ulrich JC, Wagner CD, Vanderwall DE, Waterson AG, Williams JD, White WL, Uehling DE. Wood ER, et al. Among authors: vanderwall de. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2773-8. doi: 10.1073/pnas.0708281105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287036 Free PMC article.

5

Synthesis and SAR of potent EGFR/erbB2 dual inhibitors.

Zhang YM, Cockerill S, Guntrip SB, Rusnak D, Smith K, Vanderwall D, Wood E, Lackey K. Zhang YM, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):111-4. doi: 10.1016/j.bmcl.2003.10.010. Bioorg Med Chem Lett. 2004. PMID: 14684309

6

Sequence-specific isotope effects on the cleavage of DNA by bleomycin.

Kozarich JW, Worth L Jr, Frank BL, Christner DF, Vanderwall DE, Stubbe J. Kozarich JW, et al. Among authors: vanderwall de. Science. 1989 Sep 22;245(4924):1396-9. doi: 10.1126/science.2476851. Science. 1989. PMID: 2476851

7

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors.

Rheault TR, Caferro TR, Dickerson SH, Donaldson KH, Gaul MD, Goetz AS, Mullin RJ, McDonald OB, Petrov KG, Rusnak DW, Shewchuk LM, Spehar GM, Truesdale AT, Vanderwall DE, Wood ER, Uehling DE. Rheault TR, et al. Among authors: vanderwall de. Bioorg Med Chem Lett. 2009 Feb 1;19(3):817-20. doi: 10.1016/j.bmcl.2008.12.011. Epub 2008 Dec 7. Bioorg Med Chem Lett. 2009. PMID: 19111461

8

Functional antagonism of IL-1alpha induced gene expression profiles define the cAMP/PKA pathway as a unique regulator of IL-1alpha signaling networks.

Murray DL, Johnson EN, Wang P, Gauthier J, Bing N, Vanderwall D, Xu Z, Jensen D, Cox RF, Kostura M, Sorensen SD. Murray DL, et al. J Recept Signal Transduct Res. 2009;29(5):246-56. doi: 10.1080/10799890903078473. J Recept Signal Transduct Res. 2009. PMID: 19627252

9

Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.

Toney JH, Fitzgerald PM, Grover-Sharma N, Olson SH, May WJ, Sundelof JG, Vanderwall DE, Cleary KA, Grant SK, Wu JK, Kozarich JW, Pompliano DL, Hammond GG. Toney JH, et al. Among authors: vanderwall de. Chem Biol. 1998 Apr;5(4):185-96. doi: 10.1016/s1074-5521(98)90632-9. Chem Biol. 1998. PMID: 9545432

10

Structure-activity relationships of biphenyl tetrazoles as metallo-beta-lactamase inhibitors.

Toney JH, Cleary KA, Hammond GG, Yuan X, May WJ, Hutchins SM, Ashton WT, Vanderwall DE. Toney JH, et al. Among authors: vanderwall de. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2741-6. doi: 10.1016/s0960-894x(99)00458-8. Bioorg Med Chem Lett. 1999. PMID: 10509927

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