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Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain.
Walker K, Bowes M, Panesar M, Davis A, Gentry C, Kesingland A, Gasparini F, Spooren W, Stoehr N, Pagano A, Flor PJ, Vranesic I, Lingenhoehl K, Johnson EC, Varney M, Urban L, Kuhn R. Walker K, et al. Among authors: varney m. Neuropharmacology. 2001;40(1):1-9. doi: 10.1016/s0028-3908(00)00113-1. Neuropharmacology. 2001. PMID: 11077065
(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.
Gasparini F, Bruno V, Battaglia G, Lukic S, Leonhardt T, Inderbitzin W, Laurie D, Sommer B, Varney MA, Hess SD, Johnson EC, Kuhn R, Urwyler S, Sauer D, Portet C, Schmutz M, Nicoletti F, Flor PJ. Gasparini F, et al. Among authors: varney ma. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. J Pharmacol Exp Ther. 1999. PMID: 10336568
2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
Gasparini F, Lingenhöhl K, Stoehr N, Flor PJ, Heinrich M, Vranesic I, Biollaz M, Allgeier H, Heckendorn R, Urwyler S, Varney MA, Johnson EC, Hess SD, Rao SP, Sacaan AI, Santori EM, Veliçelebi G, Kuhn R. Gasparini F, et al. Among authors: varney ma. Neuropharmacology. 1999 Oct;38(10):1493-503. doi: 10.1016/s0028-3908(99)00082-9. Neuropharmacology. 1999. PMID: 10530811
262 results