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Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors.
Filippova N, Yang X, Ananthan S, Calano J, Pathak V, Bratton L, Vekariya RH, Zhang S, Ofori E, Hayward EN, Namkoong D, Crossman DK, Crowley MR, King PH, Mobley J, Nabors LB. Filippova N, et al. Among authors: vekariya rh. Cancer Res. 2021 Apr 15;81(8):2220-2233. doi: 10.1158/0008-5472.CAN-20-2858. Epub 2021 Feb 18. Cancer Res. 2021. PMID: 33602784 Free PMC article.
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Zhu J, Quizon PM, Wang Y, Adeniran CA, Strauss MJ, Jiménez-Torres AC, Patel P, Cirino TJ, Eans SO, Hammond HR, Deliscar LS, O'Hara P, Saini SK, Ofori E, Vekariya RH, Zhang S, Moukha-Chafiq O, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhan CG, McLaughlin JP. Zhu J, et al. Among authors: vekariya rh. Neuropharmacology. 2022 Dec 1;220:109239. doi: 10.1016/j.neuropharm.2022.109239. Epub 2022 Sep 17. Neuropharmacology. 2022. PMID: 36126727
Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.
Vekariya RH, Lei W, Ray A, Saini SK, Zhang S, Molnar G, Barlow D, Karlage KL, Bilsky EJ, Houseknecht KL, Largent-Milnes TM, Streicher JM, Ananthan S. Vekariya RH, et al. J Med Chem. 2020 Jul 23;63(14):7663-7694. doi: 10.1021/acs.jmedchem.0c00503. Epub 2020 Jun 30. J Med Chem. 2020. PMID: 32530286 Free PMC article.
Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.
Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR. Chun LS, et al. Among authors: vekariya rh. Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018. Front Synaptic Neurosci. 2018. PMID: 29515433 Free PMC article.