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Year | Number of Results |
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2020 | 1 |
2022 | 2 |
2023 | 3 |
2024 | 1 |
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Page 1
Activities and binding partners of E3 ubiquitin ligase DTX3L and its roles in cancer.
Biochem Soc Trans. 2022 Dec 16;50(6):1683-1692. doi: 10.1042/BST20220501.
Biochem Soc Trans. 2022.
PMID: 36421918
Review.
Reconstitution of the DTX3L-PARP9 complex reveals determinants for high-affinity heterodimerization and multimeric assembly.
Ashok Y, Vela-Rodríguez C, Yang C, Alanen HI, Liu F, Paschal BM, Lehtiö L.
Ashok Y, et al. Among authors: vela rodriguez c.
Biochem J. 2022 Feb 11;479(3):289-304. doi: 10.1042/BCJ20210722.
Biochem J. 2022.
PMID: 35037691
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Synthetic Dual Cysteine-ADP Ribosylated Peptides from the Androgen Receptor are Recognized by the DTX3L/PARP9 Complex.
Wijngaarden S, Yang C, Vela-Rodríguez C, Lehtiö L, Overkleeft HS, Paschal BM, Filippov DV.
Wijngaarden S, et al. Among authors: vela rodriguez c.
ACS Chem Biol. 2023 Nov 17;18(11):2377-2384. doi: 10.1021/acschembio.3c00305. Epub 2023 Nov 8.
ACS Chem Biol. 2023.
PMID: 37939374
Free PMC article.
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Discovery of DTX3L inhibitors through a homogeneous FRET-based assay that monitors formation and removal of poly-ubiquitin chains.
Vela-Rodríguez C, Scarpulla I, Ashok Y, Lehtiö L.
Vela-Rodríguez C, et al.
SLAS Discov. 2023 Dec;28(8):365-375. doi: 10.1016/j.slasd.2023.08.005. Epub 2023 Aug 12.
SLAS Discov. 2023.
PMID: 37579950
Free article.
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Oligomerisation mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor.
Vela-Rodríguez C, Yang C, Alanen HI, Eki R, Abbas TA, Maksimainen MM, Glumoff T, Duman R, Wagner A, Paschal BM, Lehtiö L.
Vela-Rodríguez C, et al.
bioRxiv [Preprint]. 2023 Nov 29:2023.11.29.569193. doi: 10.1101/2023.11.29.569193.
bioRxiv. 2023.
PMID: 38076829
Free PMC article.
Updated.
Preprint.
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A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases.
Sowa ST, Vela-Rodríguez C, Galera-Prat A, Cázares-Olivera M, Prunskaite-Hyyryläinen R, Ignatev A, Lehtiö L.
Sowa ST, et al. Among authors: vela rodriguez c.
Sci Rep. 2020 Jul 23;10(1):12357. doi: 10.1038/s41598-020-69229-y.
Sci Rep. 2020.
PMID: 32704068
Free PMC article.
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Oligomerization mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor.
Vela-Rodríguez C, Yang C, Alanen HI, Eki R, Abbas TA, Maksimainen MM, Glumoff T, Duman R, Wagner A, Paschal BM, Lehtiö L.
Vela-Rodríguez C, et al.
Protein Sci. 2024 Apr;33(4):e4945. doi: 10.1002/pro.4945.
Protein Sci. 2024.
PMID: 38511494
Free PMC article.
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