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Synaptic targeting by Alzheimer's-related amyloid beta oligomers.
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Lacor PN, et al. Among authors: velasco pt. J Neurosci. 2004 Nov 10;24(45):10191-200. doi: 10.1523/JNEUROSCI.3432-04.2004. J Neurosci. 2004. PMID: 15537891 Free PMC article.
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. De Felice FG, et al. Among authors: velasco pt. Neurobiol Aging. 2008 Sep;29(9):1334-47. doi: 10.1016/j.neurobiolaging.2007.02.029. Epub 2007 Apr 2. Neurobiol Aging. 2008. PMID: 17403556 Free PMC article.
A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers.
Sebollela A, Cline EN, Popova I, Luo K, Sun X, Ahn J, Barcelos MA, Bezerra VN, Lyra E Silva NM, Patel J, Pinheiro NR, Qin LA, Kamel JM, Weng A, DiNunno N, Bebenek AM, Velasco PT, Viola KL, Lacor PN, Ferreira ST, Klein WL. Sebollela A, et al. Among authors: velasco pt. J Neurochem. 2017 Sep;142(6):934-947. doi: 10.1111/jnc.14118. Epub 2017 Aug 2. J Neurochem. 2017. PMID: 28670737 Free PMC article.
Self-assembly of Abeta(1-42) into globular neurotoxins.
Chromy BA, Nowak RJ, Lambert MP, Viola KL, Chang L, Velasco PT, Jones BW, Fernandez SJ, Lacor PN, Horowitz P, Finch CE, Krafft GA, Klein WL. Chromy BA, et al. Among authors: velasco pt. Biochemistry. 2003 Nov 11;42(44):12749-60. doi: 10.1021/bi030029q. Biochemistry. 2003. PMID: 14596589
50 results