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Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin.
Erazo-Oliveras A, Muñoz-Vega M, Mlih M, Thiriveedi V, Salinas ML, Rivera-Rodríguez JM, Kim E, Wright RC, Wang X, Landrock KK, Goldsby JS, Mullens DA, Roper J, Karpac J, Chapkin RS. Erazo-Oliveras A, et al. Among authors: thiriveedi v. Nat Commun. 2023 Jul 19;14(1):4342. doi: 10.1038/s41467-023-39640-w. Nat Commun. 2023. PMID: 37468468 Free PMC article.
The intestine is a major contributor to circulating succinate in mice.
Tong W, Hannou SA, Wang Y, Astapova I, Sargsyan A, Monn R, Thiriveedi V, Li D, McCann JR, Rawls JF, Roper J, Zhang GF, Herman MA. Tong W, et al. Among authors: thiriveedi v. FASEB J. 2022 Oct;36(10):e22546. doi: 10.1096/fj.202200135RR. FASEB J. 2022. PMID: 36106538 Free PMC article.