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Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
Chakraborty A, Tapryal N, Venkova T, Mitra J, Vasquez V, Sarker AH, Duarte-Silva S, Huai W, Ashizawa T, Ghosh G, Maciel P, Sarkar PS, Hegde ML, Chen X, Hazra TK. Chakraborty A, et al. Among authors: venkova t. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8154-8165. doi: 10.1073/pnas.1917280117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205441 Free PMC article.
Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells.
Sayed IM, Sahan AZ, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ, Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK, Das S. Sayed IM, et al. Among authors: venkova t. J Biol Chem. 2020 Aug 7;295(32):11082-11098. doi: 10.1074/jbc.RA119.009981. Epub 2020 Jun 9. J Biol Chem. 2020. PMID: 32518160 Free PMC article.