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Page 1
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation.
Science. 2023 Jan 6;379(6627):45-62. doi: 10.1126/science.abj8894. Epub 2023 Jan 5.
Science. 2023.
PMID: 36603072
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy.
Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, Mawambo GT, Howard JP, Diaz-Marin R, Parinot C, Guber V, Pilon F, Juneau R, Laflamme R, Sawchyn C, Boulay K, Leclerc S, Abu-Thuraia A, Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal JS, Mallette FA, Sapieha P.
Binet F, et al. Among authors: guber v.
Science. 2020 Aug 21;369(6506):eaay5356. doi: 10.1126/science.aay5356.
Science. 2020.
PMID: 32820093
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Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.
Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, Chaney SY, Pilon F, Dogan T, Cagnone G, Patel P, Buscarlet M, Dasgupta S, Girouard G, Rao SR, Wilson AM, O'Brien R, Juneau R, Guber V, Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P.
Crespo-Garcia S, et al. Among authors: guber v.
Cell Metab. 2021 Apr 6;33(4):818-832.e7. doi: 10.1016/j.cmet.2021.01.011. Epub 2021 Feb 5.
Cell Metab. 2021.
PMID: 33548171
Free article.
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Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life.
Hata M, Hata M, Andriessen EM, Juneau R, Pilon F, Crespo-Garcia S, Diaz-Marin R, Guber V, Binet F, Fournier F, Buscarlet M, Grou C, Calderon V, Heckel E, Melichar HJ, Joyal JS, Wilson AM, Sapieha P.
Hata M, et al. Among authors: guber v.
J Clin Invest. 2023 Feb 15;133(4):e159757. doi: 10.1172/JCI159757.
J Clin Invest. 2023.
PMID: 36787231
Free PMC article.
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NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.
Miloudi K, Oubaha M, Ménard C, Dejda A, Guber V, Cagnone G, Wilson AM, Tétreault N, Mawambo G, Binet F, Chidiac R, Delisle C, Buscarlet M, Cerani A, Crespo-Garcia S, Bentley K, Rezende F, Joyal JS, Mallette FA, Gratton JP, Larrivée B, Sapieha P.
Miloudi K, et al. Among authors: guber v.
Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4538-4547. doi: 10.1073/pnas.1814711116. Epub 2019 Feb 20.
Proc Natl Acad Sci U S A. 2019.
PMID: 30787185
Free PMC article.
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Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy.
Oubaha M, Miloudi K, Dejda A, Guber V, Mawambo G, Germain MA, Bourdel G, Popovic N, Rezende FA, Kaufman RJ, Mallette FA, Sapieha P.
Oubaha M, et al. Among authors: guber v.
Sci Transl Med. 2016 Oct 26;8(362):362ra144. doi: 10.1126/scitranslmed.aaf9440.
Sci Transl Med. 2016.
PMID: 27797960
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