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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B. Lombard DB, et al. Among authors: verdin e. Mol Cell Biol. 2007 Dec;27(24):8807-14. doi: 10.1128/MCB.01636-07. Epub 2007 Oct 8. Mol Cell Biol. 2007. PMID: 17923681 Free PMC article.
Conserved metabolic regulatory functions of sirtuins.
Schwer B, Verdin E. Schwer B, et al. Among authors: verdin e. Cell Metab. 2008 Feb;7(2):104-12. doi: 10.1016/j.cmet.2007.11.006. Cell Metab. 2008. PMID: 18249170 Free article. Review.
Acetylation of mitochondrial proteins.
Hirschey MD, Shimazu T, Huang JY, Verdin E. Hirschey MD, et al. Among authors: verdin e. Methods Enzymol. 2009;457:137-47. doi: 10.1016/S0076-6879(09)05008-3. Methods Enzymol. 2009. PMID: 19426866
Mitochondrial sirtuins.
Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. Huang JY, et al. Among authors: verdin e. Biochim Biophys Acta. 2010 Aug;1804(8):1645-51. doi: 10.1016/j.bbapap.2009.12.021. Epub 2010 Jan 7. Biochim Biophys Acta. 2010. PMID: 20060508 Review.
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. Hirschey MD, et al. Among authors: verdin e. Nature. 2010 Mar 4;464(7285):121-5. doi: 10.1038/nature08778. Nature. 2010. PMID: 20203611 Free PMC article.
Acetate metabolism and aging: An emerging connection.
Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. Shimazu T, et al. Among authors: verdin e. Mech Ageing Dev. 2010 Jul-Aug;131(7-8):511-6. doi: 10.1016/j.mad.2010.05.001. Epub 2010 May 15. Mech Ageing Dev. 2010. PMID: 20478325
337 results