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The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
Safavi S, Larouche A, Zahn A, Patenaude AM, Domanska D, Dionne K, Rognes T, Dingler F, Kang SK, Liu Y, Johnson N, Hébert J, Verdun RE, Rada CA, Vega F, Nilsen H, Di Noia JM. Safavi S, et al. Among authors: verdun re. NAR Cancer. 2020 Aug 27;2(3):zcaa019. doi: 10.1093/narcan/zcaa019. eCollection 2020 Sep. NAR Cancer. 2020. PMID: 33554121 Free PMC article.
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Zahn A, Eranki AK, Patenaude AM, Methot SP, Fifield H, Cortizas EM, Foster P, Imai K, Durandy A, Larijani M, Verdun RE, Di Noia JM. Zahn A, et al. Among authors: verdun re. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E988-97. doi: 10.1073/pnas.1320486111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591601 Free PMC article.
UNG protects B cells from AID-induced telomere loss.
Cortizas EM, Zahn A, Safavi S, Reed JA, Vega F, Di Noia JM, Verdun RE. Cortizas EM, et al. Among authors: verdun re. J Exp Med. 2016 Oct 17;213(11):2459-2472. doi: 10.1084/jem.20160635. Epub 2016 Oct 3. J Exp Med. 2016. PMID: 27697833 Free PMC article.
A licensing step links AID to transcription elongation for mutagenesis in B cells.
Methot SP, Litzler LC, Subramani PG, Eranki AK, Fifield H, Patenaude AM, Gilmore JC, Santiago GE, Bagci H, Côté JF, Larijani M, Verdun RE, Di Noia JM. Methot SP, et al. Among authors: verdun re. Nat Commun. 2018 Mar 28;9(1):1248. doi: 10.1038/s41467-018-03387-6. Nat Commun. 2018. PMID: 29593215 Free PMC article.
Erratum: The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
Safavi S, Larouche A, Zahn A, Patenaude AM, Domanska D, Dionne K, Rognes T, Dingler F, Kang SK, Liu Y, Johnson N, Hébert J, Verdun RE, Rada CA, Vega F, Nilsen H, Noia JMD. Safavi S, et al. Among authors: verdun re. NAR Cancer. 2021 Jan 6;3(1):zcaa045. doi: 10.1093/narcan/zcaa045. eCollection 2021 Mar. NAR Cancer. 2021. PMID: 34316697 Free PMC article.
Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma.
Agarwal NK, Kim CH, Kunkalla K, Konno H, Tjendra Y, Kwon D, Blonska M, Kozloski GA, Moy VT, Verdun RE, Barber GN, Lossos IS, Vega F. Agarwal NK, et al. Among authors: verdun re. Blood. 2016 Feb 4;127(5):605-15. doi: 10.1182/blood-2015-07-658781. Epub 2015 Nov 24. Blood. 2016. PMID: 26603838 Free PMC article.
Epstein-Barr virus-positive follicular lymphoma.
Mackrides N, Campuzano-Zuluaga G, Maque-Acosta Y, Moul A, Hijazi N, Ikpatt FO, Levy R, Verdun RE, Kunkalla K, Natkunam Y, Lossos IS, Vega F, Chapman J. Mackrides N, et al. Among authors: verdun re. Mod Pathol. 2017 Apr;30(4):519-529. doi: 10.1038/modpathol.2016.214. Epub 2016 Dec 16. Mod Pathol. 2017. PMID: 27982024 Free article.
LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS. Parvin S, et al. Among authors: verdun re. Cancer Cell. 2019 Sep 16;36(3):237-249.e6. doi: 10.1016/j.ccell.2019.07.007. Epub 2019 Aug 22. Cancer Cell. 2019. PMID: 31447348 Free PMC article.
46 results