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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Sadik A, Somarribas Patterson LF, Öztürk S, Mohapatra SR, Panitz V, Secker PF, Pfänder P, Loth S, Salem H, Prentzell MT, Berdel B, Iskar M, Faessler E, Reuter F, Kirst I, Kalter V, Foerster KI, Jäger E, Guevara CR, Sobeh M, Hielscher T, Poschet G, Reinhardt A, Hassel JC, Zapatka M, Hahn U, von Deimling A, Hopf C, Schlichting R, Escher BI, Burhenne J, Haefeli WE, Ishaque N, Böhme A, Schäuble S, Thedieck K, Trump S, Seiffert M, Opitz CA. Sadik A, et al. Among authors: panitz v. Cell. 2020 Sep 3;182(5):1252-1270.e34. doi: 10.1016/j.cell.2020.07.038. Epub 2020 Aug 19. Cell. 2020. PMID: 32818467 Free article.
Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging.
Abu Sammour D, Cairns JL, Boskamp T, Marsching C, Kessler T, Ramallo Guevara C, Panitz V, Sadik A, Cordes J, Schmidt S, Mohammed SA, Rittel MF, Friedrich M, Platten M, Wolf I, von Deimling A, Opitz CA, Wick W, Hopf C. Abu Sammour D, et al. Among authors: panitz v. Nat Commun. 2023 Apr 1;14(1):1823. doi: 10.1038/s41467-023-37394-z. Nat Commun. 2023. PMID: 37005414 Free PMC article.
Tryptophan metabolism in brain tumors - IDO and beyond.
Platten M, Friedrich M, Wainwright DA, Panitz V, Opitz CA. Platten M, et al. Among authors: panitz v. Curr Opin Immunol. 2021 Jun;70:57-66. doi: 10.1016/j.coi.2021.03.005. Epub 2021 Apr 1. Curr Opin Immunol. 2021. PMID: 33813026 Free PMC article. Review.
Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma.
Panitz V, Končarević S, Sadik A, Friedel D, Bausbacher T, Trump S, Farztdinov V, Schulz S, Sievers P, Schmidt S, Jürgenson I, Jung S, Kuhn K, Pflüger I, Sharma S, Wick A, Pfänder P, Selzer S, Vollmuth P, Sahm F, von Deimling A, Heiland I, Hopf C, Schulz-Knappe P, Pike I, Platten M, Wick W, Opitz CA. Panitz V, et al. Theranostics. 2021 Sep 3;11(19):9217-9233. doi: 10.7150/thno.60679. eCollection 2021. Theranostics. 2021. PMID: 34646367 Free PMC article.