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The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.
Hodgson MC, Astapova I, Cheng S, Lee LJ, Verhoeven MC, Choi E, Balk SP, Hollenberg AN. Hodgson MC, et al. Among authors: verhoeven mc. J Biol Chem. 2005 Feb 25;280(8):6511-9. doi: 10.1074/jbc.M408972200. Epub 2004 Dec 14. J Biol Chem. 2005. PMID: 15598662 Free article.
Dominant-negative ALK2 allele associates with congenital heart defects.
Smith KA, Joziasse IC, Chocron S, van Dinther M, Guryev V, Verhoeven MC, Rehmann H, van der Smagt JJ, Doevendans PA, Cuppen E, Mulder BJ, Ten Dijke P, Bakkers J. Smith KA, et al. Among authors: verhoeven mc. Circulation. 2009 Jun 23;119(24):3062-9. doi: 10.1161/CIRCULATIONAHA.108.843714. Epub 2009 Jun 8. Circulation. 2009. PMID: 19506109
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