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Page 1
Mitochondria metabolism sets the species-specific tempo of neuronal development.
Iwata R, Casimir P, Erkol E, Boubakar L, Planque M, Gallego López IM, Ditkowska M, Gaspariunaite V, Beckers S, Remans D, Vints K, Vandekeere A, Poovathingal S, Bird M, Vlaeminck I, Creemers E, Wierda K, Corthout N, Vermeersch P, Carpentier S, Davie K, Mazzone M, Gounko NV, Aerts S, Ghesquière B, Fendt SM, Vanderhaeghen P. Iwata R, et al. Among authors: vermeersch p. Science. 2023 Feb 10;379(6632):eabn4705. doi: 10.1126/science.abn4705. Epub 2023 Feb 10. Science. 2023. PMID: 36705539
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.
Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, Christen S, Dong X, Kuenen S, Voordeckers K, Verstreken P, Cassiman D, Vermeersch P, Verfaillie C, Hiller K, Fendt SM. Lorendeau D, et al. Among authors: vermeersch p. Metab Eng. 2017 Sep;43(Pt B):187-197. doi: 10.1016/j.ymben.2016.11.005. Epub 2016 Nov 12. Metab Eng. 2017. PMID: 27847310
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: vermeersch p. Leukemia. 2019 Feb;33(2):319-332. doi: 10.1038/s41375-018-0176-z. Epub 2018 Jun 21. Leukemia. 2019. PMID: 29930300 Free PMC article.
Measuring Rates of ATP Synthesis.
Bird MJ, Radenkovic S, Vermeersch P, Cassiman D. Bird MJ, et al. Among authors: vermeersch p. Methods Mol Biol. 2019;1862:97-107. doi: 10.1007/978-1-4939-8769-6_7. Methods Mol Biol. 2019. PMID: 30315462
Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Fancello L, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: vermeersch p. Leukemia. 2019 Apr;33(4):1055-1062. doi: 10.1038/s41375-019-0424-x. Leukemia. 2019. PMID: 30850735 Free PMC article.
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt SM, De Keersmaecker K. Kampen KR, et al. Among authors: vermeersch p. Nat Commun. 2019 Jun 11;10(1):2542. doi: 10.1038/s41467-019-10508-2. Nat Commun. 2019. PMID: 31186416 Free PMC article.
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth.
Geeraerts SL, Kampen KR, Rinaldi G, Gupta P, Planque M, Louros N, Heylen E, De Cremer K, De Brucker K, Vereecke S, Verbelen B, Vermeersch P, Schymkowitz J, Rousseau F, Cassiman D, Fendt SM, Voet A, Cammue BPA, Thevissen K, De Keersmaecker K. Geeraerts SL, et al. Among authors: vermeersch p. Mol Cancer Ther. 2021 Jan;20(1):50-63. doi: 10.1158/1535-7163.MCT-20-0480. Epub 2020 Nov 17. Mol Cancer Ther. 2021. PMID: 33203732 Free PMC article.
Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction.
Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B. Adant I, et al. Among authors: vermeersch p. Mol Metab. 2022 Sep;63:101537. doi: 10.1016/j.molmet.2022.101537. Epub 2022 Jun 27. Mol Metab. 2022. PMID: 35772644 Free PMC article.
The Metabolic Map into the Pathomechanism and Treatment of PGM1-CDG.
Radenkovic S, Bird MJ, Emmerzaal TL, Wong SY, Felgueira C, Stiers KM, Sabbagh L, Himmelreich N, Poschet G, Windmolders P, Verheijen J, Witters P, Altassan R, Honzik T, Eminoglu TF, James PM, Edmondson AC, Hertecant J, Kozicz T, Thiel C, Vermeersch P, Cassiman D, Beamer L, Morava E, Ghesquière B. Radenkovic S, et al. Among authors: vermeersch p. Am J Hum Genet. 2019 May 2;104(5):835-846. doi: 10.1016/j.ajhg.2019.03.003. Epub 2019 Apr 11. Am J Hum Genet. 2019. PMID: 30982613 Free PMC article.
357 results