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2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines.
De Vita S, Meninno S, Capasso L, Colarusso E, Chini MG, Lauro G, Rinaldi R, De Cicco A, Sian V, Terracciano S, Nebbioso A, Lattanzi A, Bifulco G. De Vita S, et al. Among authors: sian v. Bioorg Med Chem. 2023 Oct 1;93:117444. doi: 10.1016/j.bmc.2023.117444. Epub 2023 Aug 12. Bioorg Med Chem. 2023. PMID: 37611334 Free article.
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells.
Di Bello E, Sian V, Bontempi G, Zwergel C, Fioravanti R, Noce B, Castiello C, Tomassi S, Corinti D, Passeri D, Pellicciari R, Mercurio C, Varasi M, Altucci L, Tripodi M, Strippoli R, Nebbioso A, Valente S, Mai A. Di Bello E, et al. Among authors: sian v. Eur J Med Chem. 2023 Feb 5;247:115022. doi: 10.1016/j.ejmech.2022.115022. Epub 2022 Dec 15. Eur J Med Chem. 2023. PMID: 36549114