Vervoort SJ - Search Results

1

Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies.

Nüssing S, House IG, Kearney CJ, Chen AXY, Vervoort SJ, Beavis PA, Oliaro J, Johnstone RW, Trapani JA, Parish IA. Nüssing S, et al. Among authors: vervoort sj. J Immunol. 2020 Apr 15;204(8):2308-2315. doi: 10.4049/jimmunol.1901396. Epub 2020 Mar 9. J Immunol. 2020. PMID: 32152070

2

BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.

Hogg SJ, Newbold A, Vervoort SJ, Cluse LA, Martin BP, Gregory GP, Lefebure M, Vidacs E, Tothill RW, Bradner JE, Shortt J, Johnstone RW. Hogg SJ, et al. Among authors: vervoort sj. Mol Cancer Ther. 2016 Sep;15(9):2030-41. doi: 10.1158/1535-7163.MCT-15-0924. Epub 2016 Jul 12. Mol Cancer Ther. 2016. PMID: 27406984

3

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

Hogg SJ, Vervoort SJ, Deswal S, Ott CJ, Li J, Cluse LA, Beavis PA, Darcy PK, Martin BP, Spencer A, Traunbauer AK, Sadovnik I, Bauer K, Valent P, Bradner JE, Zuber J, Shortt J, Johnstone RW. Hogg SJ, et al. Among authors: vervoort sj. Cell Rep. 2017 Feb 28;18(9):2162-2174. doi: 10.1016/j.celrep.2017.02.011. Cell Rep. 2017. PMID: 28249162 Free PMC article.

4

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2⁺ Tumors.

Medon M, Vidacs E, Vervoort SJ, Li J, Jenkins MR, Ramsbottom KM, Trapani JA, Smyth MJ, Darcy PK, Atadja PW, Henderson MA, Johnstone RW, Haynes NM. Medon M, et al. Among authors: vervoort sj. Cancer Res. 2017 May 15;77(10):2594-2606. doi: 10.1158/0008-5472.CAN-16-2247. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249907

5

A pharmacogenomic approach validates AG-221 as an effective and on-target therapy in IDH2 mutant AML.

Kats LM, Vervoort SJ, Cole R, Rogers AJ, Gregory GP, Vidacs E, Li J, Nagaraja R, Yen KE, Johnstone RW. Kats LM, et al. Among authors: vervoort sj. Leukemia. 2017 Jun;31(6):1466-1470. doi: 10.1038/leu.2017.84. Epub 2017 Mar 10. Leukemia. 2017. PMID: 28280273 No abstract available.

6

DOCK8 Drives Src-Dependent NK Cell Effector Function.

Kearney CJ, Vervoort SJ, Ramsbottom KM, Freeman AJ, Michie J, Peake J, Casanova JL, Picard C, Tangye SG, Ma CS, Johnstone RW, Randall KL, Oliaro J. Kearney CJ, et al. Among authors: vervoort sj. J Immunol. 2017 Aug 9:ji1700751. doi: 10.4049/jimmunol.1700751. Online ahead of print. J Immunol. 2017. PMID: 28794229

7

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

Waibel M, Vervoort SJ, Kong IY, Heinzel S, Ramsbottom KM, Martin BP, Hawkins ED, Johnstone RW. Waibel M, et al. Among authors: vervoort sj. Leukemia. 2018 Jan;32(1):237-241. doi: 10.1038/leu.2017.282. Epub 2017 Sep 15. Leukemia. 2018. PMID: 28914259 No abstract available.

8

Tumor immune evasion arises through loss of TNF sensitivity.

Kearney CJ, Vervoort SJ, Hogg SJ, Ramsbottom KM, Freeman AJ, Lalaoui N, Pijpers L, Michie J, Brown KK, Knight DA, Sutton V, Beavis PA, Voskoboinik I, Darcy PK, Silke J, Trapani JA, Johnstone RW, Oliaro J. Kearney CJ, et al. Among authors: vervoort sj. Sci Immunol. 2018 May 18;3(23):eaar3451. doi: 10.1126/sciimmunol.aar3451. Sci Immunol. 2018. PMID: 29776993

9

JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias.

Kim SK, Knight DA, Jones LR, Vervoort S, Ng AP, Seymour JF, Bradner JE, Waibel M, Kats L, Johnstone RW. Kim SK, et al. Genes Dev. 2018 Jun 1;32(11-12):849-864. doi: 10.1101/gad.307504.117. Epub 2018 Jun 15. Genes Dev. 2018. PMID: 29907650 Free PMC article.

10

Antagonism of IAPs Enhances CAR T-cell Efficacy.

Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J. Michie J, et al. Among authors: vervoort sj. Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16. Cancer Immunol Res. 2019. PMID: 30651288

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