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Expression of a suicidal gene under control of the human secreted protein acidic and rich in cysteine (SPARC) promoter in tumor or stromal cells led to the inhibition of tumor cell growth.
Lopez MV, Blanco P, Viale DL, Cafferata EG, Carbone C, Gould D, Chernajovsky Y, Podhajcer OL. Lopez MV, et al. Among authors: viale dl. Mol Cancer Ther. 2006 Oct;5(10):2503-11. doi: 10.1158/1535-7163.MCT-06-0286. Mol Cancer Ther. 2006. PMID: 17041094 Free PMC article.
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
Lopez MV, Rivera AA, Viale DL, Benedetti L, Cuneo N, Kimball KJ, Wang M, Douglas JT, Zhu ZB, Bravo AI, Gidekel M, Alvarez RD, Curiel DT, Podhajcer OL. Lopez MV, et al. Among authors: viale dl. Mol Ther. 2012 Dec;20(12):2222-33. doi: 10.1038/mt.2012.147. Epub 2012 Sep 4. Mol Ther. 2012. PMID: 22948673 Free PMC article.
Cross-protection and cross-neutralization capacity of ancestral and VOC-matched SARS-CoV-2 adenoviral vector-based vaccines.
Vinzón SE, Lopez MV, Cafferata EGA, Soto AS, Berguer PM, Vazquez L, Nusblat L, Pontoriero AV, Belotti EM, Salvetti NR, Viale DL, Vilardo AE, Avaro MM, Benedetti E, Russo ML, Dattero ME, Carobene M, Sánchez-Lamas M, Afonso J, Heitrich M, Cristófalo AE, Otero LH, Baumeister EG, Ortega HH, Edelstein A, Podhajcer OL. Vinzón SE, et al. Among authors: viale dl. NPJ Vaccines. 2023 Oct 4;8(1):149. doi: 10.1038/s41541-023-00737-4. NPJ Vaccines. 2023. PMID: 37794010 Free PMC article.
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