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Page 1
Cardioprotection and lifespan extension by the natural polyamine spermidine.
Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: herbst v. Nat Med. 2016 Dec;22(12):1428-1438. doi: 10.1038/nm.4222. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841876 Free PMC article.
Dietary spermidine for lowering high blood pressure.
Eisenberg T, Abdellatif M, Zimmermann A, Schroeder S, Pendl T, Harger A, Stekovic S, Schipke J, Magnes C, Schmidt A, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Carmona-Gutierrez D, Pietrocola F, Pieber TR, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: herbst v. Autophagy. 2017 Apr 3;13(4):767-769. doi: 10.1080/15548627.2017.1280225. Epub 2017 Jan 24. Autophagy. 2017. PMID: 28118075 Free PMC article.
Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Ljubojević-Holzer S, Kraler S, Djalinac N, Abdellatif M, Voglhuber J, Schipke J, Schmidt M, Kling KM, Franke GT, Herbst V, Zirlik A, von Lewinski D, Scherr D, Rainer PP, Kohlhaas M, Nickel A, Mühlfeld C, Maack C, Sedej S. Ljubojević-Holzer S, et al. Among authors: herbst v. Cardiovasc Res. 2022 May 6;118(6):1492-1505. doi: 10.1093/cvr/cvab112. Cardiovasc Res. 2022. PMID: 33752242 Free PMC article.
Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.
Manninger M, Zweiker D, van Hunnik A, Alogna A, Prassl AJ, Schipke J, Zeemering S, Zirngast B, Schönleitner P, Schwarzl M, Herbst V, Thon-Gutschi E, Huber S, Rohrer U, Ebner J, Brussee H, Pieske BM, Heinzel FR, Verheule S, Antoons G, Lueger A, Mühlfeld C, Plank G, Schotten U, Post H, Scherr D. Manninger M, et al. Among authors: herbst v. Heart Rhythm. 2018 Sep;15(9):1328-1336. doi: 10.1016/j.hrthm.2018.05.016. Epub 2018 May 23. Heart Rhythm. 2018. PMID: 29803020