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Focused Transhepatic Electroporation Mediated by Hypersaline Infusion through the Portal Vein in Rat Model. Preliminary Results on Differential Conductivity.
Pañella C, Castellví Q, Moll X, Quesada R, Villanueva A, Iglesias M, Naranjo D, Sánchez-Velázquez P, Andaluz A, Grande L, Ivorra A, Burdío F. Pañella C, et al. Among authors: villanueva a. Radiol Oncol. 2017 Nov 29;51(4):415-421. doi: 10.1515/raon-2017-0051. eCollection 2017 Dec. Radiol Oncol. 2017. PMID: 29333120 Free PMC article.
BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.
Margalef P, Colomer C, Villanueva A, Montagut C, Iglesias M, Bellosillo B, Salazar R, Martínez-Iniesta M, Bigas A, Espinosa L. Margalef P, et al. Among authors: villanueva a. Sci Signal. 2015 Apr 21;8(373):ra38. doi: 10.1126/scisignal.2005886. Sci Signal. 2015. PMID: 25900832
Irreversible electroporation of the liver: is there a safe limit to the ablation volume?
Sánchez-Velázquez P, Castellví Q, Villanueva A, Quesada R, Pañella C, Cáceres M, Dorcaratto D, Andaluz A, Moll X, Trujillo M, Burdío JM, Berjano E, Grande L, Ivorra A, Burdío F. Sánchez-Velázquez P, et al. Among authors: villanueva a. Sci Rep. 2016 Apr 1;6:23781. doi: 10.1038/srep23781. Sci Rep. 2016. PMID: 27032535 Free PMC article.
IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.
Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Solé L, González-Farré M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borràs E, Iglesias M, Sabidó E, Bigas A, Boulton SJ, Espinosa L. Colomer C, et al. Among authors: villanueva a. Mol Cell. 2019 Aug 22;75(4):669-682.e5. doi: 10.1016/j.molcel.2019.05.036. Epub 2019 Jul 10. Mol Cell. 2019. PMID: 31302002 Free PMC article.
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair.
Alonso-Marañón J, Villanueva A, Piulats JM, Martínez-Iniesta M, Solé L, Martín-Liberal J, Segura S, Pujol RM, Iglesias M, Bigas A, Gallardo F, Espinosa L. Alonso-Marañón J, et al. Among authors: villanueva a. Oncogene. 2021 Aug;40(31):5042-5048. doi: 10.1038/s41388-021-01879-2. Epub 2021 Jun 17. Oncogene. 2021. PMID: 34140639
A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer.
Margalef P, Fernández-Majada V, Villanueva A, Garcia-Carbonell R, Iglesias M, López L, Martínez-Iniesta M, Villà-Freixa J, Mulero MC, Andreu M, Torres F, Mayo MW, Bigas A, Espinosa L. Margalef P, et al. Among authors: villanueva a. Cell Rep. 2012 Oct 25;2(4):840-54. doi: 10.1016/j.celrep.2012.08.028. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041317 Free article.
Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.
López-Arribillaga E, Rodilla V, Colomer C, Vert A, Shelton A, Cheng JH, Yan B, Gonzalez-Perez A, Junttila MR, Iglesias M, Torres F, Albanell J, Villanueva A, Bigas A, Siebel CW, Espinosa L. López-Arribillaga E, et al. Among authors: villanueva a. Nat Commun. 2018 Jul 31;9(1):2992. doi: 10.1038/s41467-018-05385-0. Nat Commun. 2018. PMID: 30065304 Free PMC article.
p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Solé L, Lobo-Jarne T, Álvarez-Villanueva D, Alonso-Marañón J, Guillén Y, Guix M, Sangrador I, Rozalén C, Vert A, Barbachano A, Lop J, Salido M, Bellosillo B, García-Romero R, Garrido M, González J, Martínez-Iniesta M, López-Arribillaga E, Salazar R, Montagut C, Torres F, Iglesias M, Celià-Terrassa T, Muñoz A, Villanueva A, Bigas A, Espinosa L. Solé L, et al. Among authors: villanueva a. Nat Commun. 2022 May 23;13(1):2866. doi: 10.1038/s41467-022-30382-9. Nat Commun. 2022. PMID: 35606354 Free PMC article.
Differences between CAFs and their paired NCF from adjacent colonic mucosa reveal functional heterogeneity of CAFs, providing prognostic information.
Berdiel-Acer M, Sanz-Pamplona R, Calon A, Cuadras D, Berenguer A, Sanjuan X, Paules MJ, Salazar R, Moreno V, Batlle E, Villanueva A, Molleví DG. Berdiel-Acer M, et al. Among authors: villanueva a. Mol Oncol. 2014 Oct;8(7):1290-305. doi: 10.1016/j.molonc.2014.04.006. Epub 2014 May 6. Mol Oncol. 2014. PMID: 24839936 Free PMC article.
895 results