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Slc7a9-deficient mice develop cystinuria non-I and cystine urolithiasis.
Feliubadaló L, Arbonés ML, Mañas S, Chillarón J, Visa J, Rodés M, Rousaud F, Zorzano A, Palacín M, Nunes V. Feliubadaló L, et al. Among authors: visa j. Hum Mol Genet. 2003 Sep 1;12(17):2097-108. doi: 10.1093/hmg/ddg228. Epub 2003 Jul 15. Hum Mol Genet. 2003. PMID: 12915471
Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin.
Cufí S, Corominas-Faja B, Lopez-Bonet E, Bonavia R, Pernas S, López IÁ, Dorca J, Martínez S, López NB, Fernández SD, Cuyàs E, Visa J, Rodríguez-Gallego E, Quirantes-Piné R, Segura-Carretero A, Joven J, Martin-Castillo B, Menendez JA. Cufí S, et al. Among authors: visa j. Oncotarget. 2013 Sep;4(9):1484-95. doi: 10.18632/oncotarget.1234. Oncotarget. 2013. PMID: 23986086 Free PMC article.
Slc7a9 knockout mouse is a good cystinuria model for antilithiasic pharmacological studies.
Font-Llitjós M, Feliubadaló L, Espino M, Clèries R, Mañas S, Frey IM, Puertas S, Colell G, Palomo S, Aranda J, Visa J, Palacín M, Nunes V. Font-Llitjós M, et al. Among authors: visa j. Am J Physiol Renal Physiol. 2007 Sep;293(3):F732-40. doi: 10.1152/ajprenal.00121.2007. Epub 2007 Jun 27. Am J Physiol Renal Physiol. 2007. PMID: 17596531 Free article.
Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells.
Cufí S, Bonavia R, Vazquez-Martin A, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, Barrajón-Catalán E, Visa J, Segura-Carretero A, Bosch-Barrera J, Joven J, Micol V, Menendez JA. Cufí S, et al. Among authors: visa j. Food Chem Toxicol. 2013 Oct;60:360-8. doi: 10.1016/j.fct.2013.07.063. Epub 2013 Aug 1. Food Chem Toxicol. 2013. PMID: 23916468
157 results