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Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.
Yun H, Narayan N, Vohra S, Giotopoulos G, Mupo A, Madrigal P, Sasca D, Lara-Astiaso D, Horton SJ, Agrawal-Singh S, Meduri E, Basheer F, Marando L, Gozdecka M, Dovey OM, Castillo-Venzor A, Wang X, Gallipoli P, Müller-Tidow C, Osborne CS, Vassiliou GS, Huntly BJP. Yun H, et al. Among authors: vohra s. Nat Genet. 2021 Oct;53(10):1443-1455. doi: 10.1038/s41588-021-00925-9. Epub 2021 Sep 23. Nat Genet. 2021. PMID: 34556857 Free PMC article.
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition.
Gallipoli P, Giotopoulos G, Tzelepis K, Costa ASH, Vohra S, Medina-Perez P, Basheer F, Marando L, Di Lisio L, Dias JML, Yun H, Sasca D, Horton SJ, Vassiliou G, Frezza C, Huntly BJP. Gallipoli P, et al. Among authors: vohra s. Blood. 2018 Apr 12;131(15):1639-1653. doi: 10.1182/blood-2017-12-820035. Epub 2018 Feb 20. Blood. 2018. PMID: 29463564 Free PMC article.
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
Horton SJ, Giotopoulos G, Yun H, Vohra S, Sheppard O, Bashford-Rogers R, Rashid M, Clipson A, Chan WI, Sasca D, Yiangou L, Osaki H, Basheer F, Gallipoli P, Burrows N, Erdem A, Sybirna A, Foerster S, Zhao W, Sustic T, Petrunkina Harrison A, Laurenti E, Okosun J, Hodson D, Wright P, Smith KG, Maxwell P, Fitzgibbon J, Du MQ, Adams DJ, Huntly BJP. Horton SJ, et al. Among authors: vohra s. Nat Cell Biol. 2017 Sep;19(9):1093-1104. doi: 10.1038/ncb3597. Epub 2017 Aug 21. Nat Cell Biol. 2017. PMID: 28825697 Free PMC article.
Estimated public health impact of concurrent mask mandate and vaccinate-or-test requirement in Illinois, October to December 2021.
Castonguay FM, Barnes A, Jeon S, Fornoff J, Adhikari BB, Fischer LS, Greening B Jr, Hassan AO, Kahn EB, Kang GJ, Kauerauf J, Patrick S, Vohra S, Meltzer MI. Castonguay FM, et al. Among authors: vohra s. BMC Public Health. 2024 Apr 12;24(1):1013. doi: 10.1186/s12889-024-18203-8. BMC Public Health. 2024. PMID: 38609903 Free PMC article.
The UK Divide: Does Having a Pembrolizumab-Chemotherapy Option in Head and Neck Cancer Matter? Real-world Experience of First-line Palliative Pembrolizumab Monotherapy and Pembrolizumab-Chemotherapy Combination in Scotland.
Thapa A, Cowell A, Peters A, Noble DJ, James A, Lamb C, Grose D, Vohra S, Schipani S, Mactier K, Mackenzie J, Srinivasan D, Laws K, Moleron R, Niblock P, Soh FY, Paterson C, Wilson C. Thapa A, et al. Among authors: vohra s. Clin Oncol (R Coll Radiol). 2024 May;36(5):287-299. doi: 10.1016/j.clon.2024.02.004. Epub 2024 Feb 12. Clin Oncol (R Coll Radiol). 2024. PMID: 38395634
467 results