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Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism.
Nat Commun. 2023 May 24;14(1):2847. doi: 10.1038/s41467-023-38501-w.
Nat Commun. 2023.
PMID: 37225734
Free PMC article.
Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites.
Bretou M, Sannerud R, Escamilla-Ayala A, Leroy T, Vrancx C, Van Acker ZP, Perdok A, Vermeire W, Vorsters I, Van Keymolen S, Maxson M, Pavie B, Wierda K, Eskelinen EL, Annaert W.
Bretou M, et al. Among authors: vorsters i.
Dev Cell. 2024 Apr 12:S1534-5807(24)00199-0. doi: 10.1016/j.devcel.2024.03.030. Online ahead of print.
Dev Cell. 2024.
PMID: 38626765
Free article.
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