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The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.
Wijers M, Zanoni P, Liv N, Vos DY, Jäckstein MY, Smit M, Wilbrink S, Wolters JC, van der Veen YT, Huijkman N, Dekker D, Kloosterhuis N, van Dijk TH, Billadeau DD, Kuipers F, Klumperman J, von Eckardstein A, Kuivenhoven JA, van de Sluis B. Wijers M, et al. Among authors: vos dy. JCI Insight. 2019 Jun 6;4(11):e126462. doi: 10.1172/jci.insight.126462. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167970 Free PMC article.
Recycling the LDL receptor to combat atherosclerosis.
Vos D, Kuivenhoven JA, van de Sluis B. Vos D, et al. Aging (Albany NY). 2018 Nov 27;10(12):3638-3640. doi: 10.18632/aging.101681. Aging (Albany NY). 2018. PMID: 30482888 Free PMC article. No abstract available.
Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins.
Vos DY, Wijers M, Smit M, Huijkman N, Kloosterhuis NJ, Wolters JC, Tissink JJ, Pronk ACM, Kooijman S, Rensen PCN, Kuivenhoven JA, van de Sluis B. Vos DY, et al. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):e29-e45. doi: 10.1161/ATVBAHA.122.318169. Epub 2022 Nov 10. Arterioscler Thromb Vasc Biol. 2023. PMID: 36353989 Free article.
Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure.
Byrne NJ, Matsumura N, Maayah ZH, Ferdaoussi M, Takahara S, Darwesh AM, Levasseur JL, Jahng JWS, Vos D, Parajuli N, El-Kadi AOS, Braam B, Young ME, Verma S, Light PE, Sweeney G, Seubert JM, Dyck JRB. Byrne NJ, et al. Circ Heart Fail. 2020 Jan;13(1):e006277. doi: 10.1161/CIRCHEARTFAILURE.119.006277. Epub 2020 Jan 20. Circ Heart Fail. 2020. PMID: 31957470
Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure.
Byrne NJ, Soni S, Takahara S, Ferdaoussi M, Al Batran R, Darwesh AM, Levasseur JL, Beker D, Vos DY, Schmidt MA, Alam AS, Maayah ZH, Schertzer JD, Seubert JM, Ussher JR, Dyck JRB. Byrne NJ, et al. Among authors: vos dy. Circ Heart Fail. 2020 Jun;13(6):e006573. doi: 10.1161/CIRCHEARTFAILURE.119.006573. Epub 2020 Jun 4. Circ Heart Fail. 2020. PMID: 32493060