Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Yue QK, Kass IJ, Sampson NS, Vrielink A.
Yue QK, et al. Among authors: vrielink a.
Biochemistry. 1999 Apr 6;38(14):4277-86. doi: 10.1021/bi982497j.
Biochemistry. 1999.
PMID: 10194345
Cholesterol oxidase is a monomeric flavoenzyme which catalyzes the oxidation and isomerization of cholesterol to cholest-4-en-3-one. ...The X-ray structure of the enzyme from Brevibacterium sterolicum revealed two loops, comprising residues 78-87 and residues 433-436, whic …
Cholesterol oxidase is a monomeric flavoenzyme which catalyzes the oxidation and isomerization of cholesterol to cholest-4-en-3-one. …