Waddington SN - Search Results

1

LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives.

Al-Allaf FA, Coutelle C, Waddington SN, David AL, Harbottle R, Themis M. Al-Allaf FA, et al. Among authors: waddington sn. Int Arch Med. 2010 Dec 13;3:36. doi: 10.1186/1755-7682-3-36. Int Arch Med. 2010. PMID: 21144047 Free PMC article.

2

Sustained delivery of therapeutic concentrations of human clotting factor IX--a comparison of adenoviral and AAV vectors administered in utero.

Schneider H, Mühle C, Douar AM, Waddington S, Jiang QJ, von der Mark K, Coutelle C, Rascher W. Schneider H, et al. J Gene Med. 2002 Jan-Feb;4(1):46-53. doi: 10.1002/jgm.233. J Gene Med. 2002. PMID: 11828387

3

Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero.

David A, Cook T, Waddington S, Peebles D, Nivsarkar M, Knapton H, Miah M, Dahse T, Noakes D, Schneider H, Rodeck C, Coutelle C, Themis M. David A, et al. Hum Gene Ther. 2003 Mar 1;14(4):353-64. doi: 10.1089/104303403321208952. Hum Gene Ther. 2003. PMID: 12659676

4

Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice.

Waddington SN, Mitrophanous KA, Ellard FM, Buckley SM, Nivsarkar M, Lawrence L, Cook HT, Al-Allaf F, Bigger B, Kingsman SM, Coutelle C, Themis M. Waddington SN, et al. Gene Ther. 2003 Aug;10(15):1234-40. doi: 10.1038/sj.gt.3301991. Gene Ther. 2003. PMID: 12858188

5

The hopes and fears of in utero gene therapy for genetic disease--a review.

Coutelle C, Themis M, Waddington S, Gregory L, Nivsarkar M, Buckley S, Cook T, Rodeck C, Peebles D, David A. Coutelle C, et al. Placenta. 2003 Oct;24 Suppl B:S114-21. doi: 10.1016/s0143-4004(03)00140-1. Placenta. 2003. PMID: 14559040 Review.

6

Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero.

Peebles D, Gregory LG, David A, Themis M, Waddington SN, Knapton HJ, Miah M, Cook T, Lawrence L, Nivsarkar M, Rodeck C, Coutelle C. Peebles D, et al. Among authors: waddington sn. Gene Ther. 2004 Jan;11(1):70-8. doi: 10.1038/sj.gt.3302130. Gene Ther. 2004. PMID: 14681699

7

Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus.

Waddington SN, Buckley SM, Bernloehr C, Bossow S, Ungerechts G, Cook T, Gregory L, Rahim A, Themis M, Neubert WJ, Coutelle C, Lauer UM, Bitzer M. Waddington SN, et al. Gene Ther. 2004 Apr;11(7):599-608. doi: 10.1038/sj.gt.3302205. Gene Ther. 2004. PMID: 14724676

8

Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy.

Gregory LG, Waddington SN, Holder MV, Mitrophanous KA, Buckley SM, Mosley KL, Bigger BW, Ellard FM, Walmsley LE, Lawrence L, Al-Allaf F, Kingsman S, Coutelle C, Themis M. Gregory LG, et al. Among authors: waddington sn. Gene Ther. 2004 Jul;11(14):1117-25. doi: 10.1038/sj.gt.3302268. Gene Ther. 2004. PMID: 15141156

9

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.

Waddington SN, Nivsarkar MS, Mistry AR, Buckley SM, Kemball-Cook G, Mosley KL, Mitrophanous K, Radcliffe P, Holder MV, Brittan M, Georgiadis A, Al-Allaf F, Bigger BW, Gregory LG, Cook HT, Ali RR, Thrasher A, Tuddenham EG, Themis M, Coutelle C. Waddington SN, et al. Blood. 2004 Nov 1;104(9):2714-21. doi: 10.1182/blood-2004-02-0627. Epub 2004 Jul 1. Blood. 2004. PMID: 15231566 Free article.

10

Fetal and neonatal gene therapy: benefits and pitfalls.

Waddington SN, Kennea NL, Buckley SM, Gregory LG, Themis M, Coutelle C. Waddington SN, et al. Gene Ther. 2004 Oct;11 Suppl 1:S92-7. doi: 10.1038/sj.gt.3302375. Gene Ther. 2004. PMID: 15454963 Review.

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