Wajant H - Search Results

1

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.

Engels IH, Stepczynska A, Stroh C, Lauber K, Berg C, Schwenzer R, Wajant H, Jänicke RU, Porter AG, Belka C, Gregor M, Schulze-Osthoff K, Wesselborg S. Engels IH, et al. Among authors: wajant h. Oncogene. 2000 Sep 21;19(40):4563-73. doi: 10.1038/sj.onc.1203824. Oncogene. 2000. PMID: 11030145

2

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction.

Wajant H, Johannes FJ, Haas E, Siemienski K, Schwenzer R, Schubert G, Weiss T, Grell M, Scheurich P. Wajant H, et al. Curr Biol. 1998 Jan 15;8(2):113-6. doi: 10.1016/s0960-9822(98)70042-9. Curr Biol. 1998. PMID: 9427646 Free article.

3

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways.

Mühlenbeck F, Haas E, Schwenzer R, Schubert G, Grell M, Smith C, Scheurich P, Wajant H. Mühlenbeck F, et al. Among authors: wajant h. J Biol Chem. 1998 Dec 4;273(49):33091-8. doi: 10.1074/jbc.273.49.33091. J Biol Chem. 1998. PMID: 9830064 Free article.

4

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

Schneider P, Schwenzer R, Haas E, Mühlenbeck F, Schubert G, Scheurich P, Tschopp J, Wajant H. Schneider P, et al. Among authors: wajant h. Eur J Immunol. 1999 Jun;29(6):1785-92. doi: 10.1002/(SICI)1521-4141(199906)29:06<1785::AID-IMMU1785>3.0.CO;2-U. Eur J Immunol. 1999. PMID: 10382740 Free article.

5

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase.

Schwenzer R, Siemienski K, Liptay S, Schubert G, Peters N, Scheurich P, Schmid RM, Wajant H. Schwenzer R, et al. Among authors: wajant h. J Biol Chem. 1999 Jul 2;274(27):19368-74. doi: 10.1074/jbc.274.27.19368. J Biol Chem. 1999. PMID: 10383449 Free article.

6

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation.

Mühlenbeck F, Schneider P, Bodmer JL, Schwenzer R, Hauser A, Schubert G, Scheurich P, Moosmayer D, Tschopp J, Wajant H. Mühlenbeck F, et al. Among authors: wajant h. J Biol Chem. 2000 Oct 13;275(41):32208-13. doi: 10.1074/jbc.M000482200. J Biol Chem. 2000. PMID: 10807904 Free article.

7

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD).

Wajant H, Haas E, Schwenzer R, Muhlenbeck F, Kreuz S, Schubert G, Grell M, Smith C, Scheurich P. Wajant H, et al. J Biol Chem. 2000 Aug 11;275(32):24357-66. doi: 10.1074/jbc.M000811200. J Biol Chem. 2000. PMID: 10823821 Free article.

8

No RISC, no fun: assembly of receptor-induced signalling complexes in the tumor necrosis factor system.

Schwenzer R, Zimmermann G, Fotin M, Wajant H, Grell M. Schwenzer R, et al. Among authors: wajant h. Eur Cytokine Netw. 2000 Sep;11(3):519-20. Eur Cytokine Netw. 2000. PMID: 11203203 Free article. No abstract available.

9

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.

Bartke T, Siegmund D, Peters N, Reichwein M, Henkler F, Scheurich P, Wajant H. Bartke T, et al. Among authors: wajant h. Oncogene. 2001 Feb 1;20(5):571-80. doi: 10.1038/sj.onc.1204124. Oncogene. 2001. PMID: 11313989

10

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

Kreuz S, Siegmund D, Scheurich P, Wajant H. Kreuz S, et al. Among authors: wajant h. Mol Cell Biol. 2001 Jun;21(12):3964-73. doi: 10.1128/MCB.21.12.3964-3973.2001. Mol Cell Biol. 2001. PMID: 11359904 Free PMC article.

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