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Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB. Schvartzman JM, et al. Among authors: walch h. Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12. Mol Cell. 2023. PMID: 37311462
Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.
Sihag S, Nussenzweig SC, Walch HS, Hsu M, Tan KS, Sanchez-Vega F, Chatila WK, De La Torre SA, Patel A, Janjigian YY, Maron S, Ku GY, Tang LH, Hechtman J, Shah PM, Wu AJ, Jones DR, Molena D, Solit DB, Schultz N, Berger MF. Sihag S, et al. Among authors: walch hs. Clin Cancer Res. 2021 Jun 15;27(12):3491-3498. doi: 10.1158/1078-0432.CCR-20-4707. Epub 2021 Apr 1. Clin Cancer Res. 2021. PMID: 33795256 Free PMC article.
Association of genomic profiles and survival in early onset and screening-age colorectal cancer patients with liver metastases resected over 15 years.
Narayan RR, Aveson VG, Chou JF, Walch HS, Sanchez-Vega F, Santos Fernandes GD, Balachandran VP, D'Angelica MI, Drebin JA, Jarnagin WR, Wei AC, Cercek A, Gönen M, Schultz N, Kingham TP. Narayan RR, et al. J Surg Oncol. 2022 Apr;125(5):880-888. doi: 10.1002/jso.26797. Epub 2022 Jan 23. J Surg Oncol. 2022. PMID: 35066881 Free PMC article.
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.
Nguyen B, Fong C, Luthra A, Smith SA, DiNatale RG, Nandakumar S, Walch H, Chatila WK, Madupuri R, Kundra R, Bielski CM, Mastrogiacomo B, Donoghue MTA, Boire A, Chandarlapaty S, Ganesh K, Harding JJ, Iacobuzio-Donahue CA, Razavi P, Reznik E, Rudin CM, Zamarin D, Abida W, Abou-Alfa GK, Aghajanian C, Cercek A, Chi P, Feldman D, Ho AL, Iyer G, Janjigian YY, Morris M, Motzer RJ, O'Reilly EM, Postow MA, Raj NP, Riely GJ, Robson ME, Rosenberg JE, Safonov A, Shoushtari AN, Tap W, Teo MY, Varghese AM, Voss M, Yaeger R, Zauderer MG, Abu-Rustum N, Garcia-Aguilar J, Bochner B, Hakimi A, Jarnagin WR, Jones DR, Molena D, Morris L, Rios-Doria E, Russo P, Singer S, Strong VE, Chakravarty D, Ellenson LH, Gopalan A, Reis-Filho JS, Weigelt B, Ladanyi M, Gonen M, Shah SP, Massague J, Gao J, Zehir A, Berger MF, Solit DB, Bakhoum SF, Sanchez-Vega F, Schultz N. Nguyen B, et al. Among authors: walch h. Cell. 2022 Feb 3;185(3):563-575.e11. doi: 10.1016/j.cell.2022.01.003. Cell. 2022. PMID: 35120664 Free PMC article.
Concurrent Germline BRCA1/2 and Mismatch Repair Mutations in Young-Onset Pancreatic and Colorectal Cancer: The Importance of Comprehensive Germline and Somatic Characterization to Inform Therapeutic Options.
Ozer M, Ranganathan M, Lecomte N, Schvartzman JM, Walch HS, Chatila WK, Hong J, Carlo MI, Walsh MF, Sheehan M, Mandelker D, Ceyhan-Birsoy O, Maio A, Kemel Y, Iacobuzio-Donahue CA, O'Reilly EM, Yu KH. Ozer M, et al. Among authors: walch hs. JCO Precis Oncol. 2022 Jun;6:e2100560. doi: 10.1200/PO.21.00560. JCO Precis Oncol. 2022. PMID: 35675575 Free PMC article. No abstract available.
82 results