Walker D - Search Results

1

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.

Xu Q, Bernardo A, Walker D, Kanegawa T, Mahley RW, Huang Y. Xu Q, et al. Among authors: walker d. J Neurosci. 2006 May 10;26(19):4985-94. doi: 10.1523/JNEUROSCI.5476-05.2006. J Neurosci. 2006. PMID: 16687490 Free PMC article.

2

Intron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS.

Xu Q, Walker D, Bernardo A, Brodbeck J, Balestra ME, Huang Y. Xu Q, et al. Among authors: walker d. J Neurosci. 2008 Feb 6;28(6):1452-9. doi: 10.1523/JNEUROSCI.3253-07.2008. J Neurosci. 2008. PMID: 18256266 Free PMC article.

3

Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice.

Bien-Ly N, Gillespie AK, Walker D, Yoon SY, Huang Y. Bien-Ly N, et al. Among authors: walker d. J Neurosci. 2012 Apr 4;32(14):4803-11. doi: 10.1523/JNEUROSCI.0033-12.2012. J Neurosci. 2012. PMID: 22492035 Free PMC article.

4

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.

Chen HK, Liu Z, Meyer-Franke A, Brodbeck J, Miranda RD, McGuire JG, Pleiss MA, Ji ZS, Balestra ME, Walker DW, Xu Q, Jeong DE, Budamagunta MS, Voss JC, Freedman SB, Weisgraber KH, Huang Y, Mahley RW. Chen HK, et al. Among authors: walker dw. J Biol Chem. 2012 Feb 17;287(8):5253-66. doi: 10.1074/jbc.M111.276162. Epub 2011 Dec 12. J Biol Chem. 2012. PMID: 22158868 Free PMC article.

5

Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in mice.

Knoferle J, Yoon SY, Walker D, Leung L, Gillespie AK, Tong LM, Bien-Ly N, Huang Y. Knoferle J, et al. Among authors: walker d. J Neurosci. 2014 Oct 15;34(42):14069-78. doi: 10.1523/JNEUROSCI.2281-14.2014. J Neurosci. 2014. PMID: 25319703 Free PMC article.

6

Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.

Wang C, Najm R, Xu Q, Jeong DE, Walker D, Balestra ME, Yoon SY, Yuan H, Li G, Miller ZA, Miller BL, Malloy MJ, Huang Y. Wang C, et al. Among authors: walker d. Nat Med. 2018 May;24(5):647-657. doi: 10.1038/s41591-018-0004-z. Epub 2018 Apr 9. Nat Med. 2018. PMID: 29632371 Free PMC article.

7

Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice.

Leung L, Andrews-Zwilling Y, Yoon SY, Jain S, Ring K, Dai J, Wang MM, Tong L, Walker D, Huang Y. Leung L, et al. Among authors: walker d. PLoS One. 2012;7(12):e53569. doi: 10.1371/journal.pone.0053569. Epub 2012 Dec 31. PLoS One. 2012. PMID: 23300939 Free PMC article.

8

Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor.

Ring KL, Tong LM, Balestra ME, Javier R, Andrews-Zwilling Y, Li G, Walker D, Zhang WR, Kreitzer AC, Huang Y. Ring KL, et al. Among authors: walker d. Cell Stem Cell. 2012 Jul 6;11(1):100-9. doi: 10.1016/j.stem.2012.05.018. Epub 2012 Jun 7. Cell Stem Cell. 2012. PMID: 22683203 Free PMC article.

9

Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development.

Jain S, Yoon SY, Zhu L, Brodbeck J, Dai J, Walker D, Huang Y. Jain S, et al. Among authors: walker d. PLoS One. 2012;7(9):e46340. doi: 10.1371/journal.pone.0046340. Epub 2012 Sep 25. PLoS One. 2012. PMID: 23050017 Free PMC article.

10

Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells.

Fong H, Wang C, Knoferle J, Walker D, Balestra ME, Tong LM, Leung L, Ring KL, Seeley WW, Karydas A, Kshirsagar MA, Boxer AL, Kosik KS, Miller BL, Huang Y. Fong H, et al. Among authors: walker d. Stem Cell Reports. 2013 Aug 29;1(3):226-34. doi: 10.1016/j.stemcr.2013.08.001. eCollection 2013. Stem Cell Reports. 2013. PMID: 24319659 Free PMC article.

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